Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:6175
Official Symbol:RPLP0
Other Aliases:L10E|MGC111226|MGC88175|P0|PRLP0|RPP0
See related:HGNC:10371|MIM:180510|HPRD:01610
Chromosome:12
Location:12q24.2
Gene Description:ribosomal protein, large, P0
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0972
ORGANISM:human
Entrez Gene ID:6175
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Downregulated
Fold Change:-1.4 :: -1.4
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
6175GO:0003723TASFunctionRNA binding
6175GO:0003735IEAFunctionstructural constituent of ribosome
6175GO:0003735TASFunctionstructural constituent of ribosome
6175GO:0005515IPIFunctionprotein binding
6175GO:0005840IEAComponentribosome
6175GO:0005842TASComponentcytosolic large ribosomal subunit (sensu Eukaryota)
6175GO:0006412TASProcessprotein biosynthesis
6175GO:0006414IEAProcesstranslational elongation
6175GO:0042254IEAProcessribosome biogenesis and assembly
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_000993.1-P09989Ribosome-inactivating protein alpha-trichosanthin precursor (rRNA N-glycosidase) (Alpha-TCS).BIND149182
NP_444505.16885NP_663304.1mitogen-activated protein kinase kinase kinase 7 isoform BHPRD04011
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
6175RLA0_HUMANP05388IPR000104Antifreeze_1Antifreeze protein, type I
6175RLA0_HUMANP05388IPR001778POA_allergen_CPollen allergen Poa pIX/Phl pVI, C-terminal
6175RLA0_HUMANP05388IPR001790Ribosomal_L10Ribosomal protein L10
6175RLA0_HUMANP05388IPR001813Ribosomal_60SRibosomal protein 60S

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