Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:6185
Official Symbol:RPN2
Other Aliases:RIBIIR|RPN-II|RPNII|SWP1
See related:HGNC:10382|MIM:180490|HPRD:01609
Chromosome:20
Location:20q12-q13.1
Gene Description:ribophorin II
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0871
ORGANISM:human
Entrez Gene ID:6185
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Downregulated
Fold Change:-1.8 :: -1.8 :: 1.1 :: -1.1
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
20014CBCerebellum29.623755455017152.9278717041016
20014CTXCerebral cortex39.816785693168639.2522505521774
20014HIPHippocampal region62.031969070434659.2958946228027
20014HPFHippocampal formation56.679519653320355.7818241119385
20014HYHypothalamus36.702123641967836.5231981277466
20014LSXLateral septal complex51.698364257812550.8919379115105
20014MBMidbrain19.388299465179420.9746346473694
20014MYMedulla31.411825656890933.6202781200409
20014OLFOlfactory bulb54.99794435501152.75017786026
20014PPons19.679417610168520.3297848701477
20014PALPallidum29.661128401756329.7296386957169
20014RHPRetrohippocampal region48.512446403503451.2462031841278
20014sAMYStriatum-like amygdalar nuclei43.450788259506239.4323143959045
20014STRStriatum29.94949543476127.333919852972
20014STRdStriatum dorsal region19.960321456193918.2064059227705
20014STRvStriatum ventral region43.254126071929936.2860170602798
20014THThalamus13.966635823249812.591095328331
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
6185GO:0004579ICFunctiondolichyl-diphosphooligosaccharide-protein glycotransferase activity
6185GO:0004579IEAFunctiondolichyl-diphosphooligosaccharide-protein glycotransferase activity
6185GO:0006464TASProcessprotein modification
6185GO:0008250IEAComponentoligosaccharyl transferase complex
6185GO:0008250TASComponentoligosaccharyl transferase complex
6185GO:0016020IEAComponentmembrane
6185GO:0016021IEAComponentintegral to membrane
6185GO:0016740IEAFunctiontransferase activity
6185GO:0018279ICProcessprotein amino acid N-linked glycosylation via asparagine
6185GO:0018279IEAProcessprotein amino acid N-linked glycosylation via asparagine
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
6185RIB2_HUMANP04844IPR008814Ribophorin_IIRibophorin II

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