Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:6327
Official Symbol:SCN2B
Other Aliases:-
See related:HGNC:10589|MIM:601327|HPRD:03208
Chromosome:11
Location:11q23
Gene Description:sodium channel, voltage-gated, type II, beta
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0388
ORGANISM:human
Entrez Gene ID:6327
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:25349
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 2
KARG ID:QTL0133
ORGANISM:human
Entrez Gene ID:6327
Evidence Type:QTL assay
Evidence ID Type:PUBMED
Evidence ID:NA
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
72821CBCerebellum100.0100.0
72821CTXCerebral cortex100.0100.0
72821HIPHippocampal region100.0100.0
72821HPFHippocampal formation100.0100.0
72821HYHypothalamus91.586311340332100.0
72821LSXLateral septal complex98.8667449951172100.0
72821MBMidbrain100.0100.0
72821MYMedulla84.1895523071289100.0
72821OLFOlfactory bulb87.4033737182617100.0
72821PPons76.6403427124023100.0
72821PALPallidum94.4636535644531100.0
72821RHPRetrohippocampal region100.0100.0
72821sAMYStriatum-like amygdalar nuclei100.0100.0
72821STRStriatum100.0100.0
72821STRdStriatum dorsal region100.0100.0
72821STRvStriatum ventral region100.0100.0
72821THThalamus100.0100.0
KARG Evidence 3
KARG ID:QTL0133
Trait:alcohol preference
Peak:26
Peak Marker:D9Mit330
Parents:(C57BL/6J x DBA/2J)F2 intercross
Evidence ID:9726281
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
6327GO:0001518TASComponentvoltage-gated sodium channel complex
6327GO:0005248TASFunctionvoltage-gated sodium channel activity
6327GO:0006811IEAProcession transport
6327GO:0006814TASProcesssodium ion transport
6327GO:0007268TASProcesssynaptic transmission
6327GO:0016020IEAComponentmembrane
6327GO:0016021IEAComponentintegral to membrane
6327GO:0031402IEAFunctionsodium ion binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
6327SCN2B_HUMANO60939IPR007110Ig-likeImmunoglobulin-like
6327SCN2B_HUMANO60939IPR000920Myelin_P0Myelin P0 protein
6327SCN2B_HUMANO60939IPR013106V-setImmunoglobulin V-set

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