Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:6330
Official Symbol:SCN4B
Other Aliases:-
See related:HGNC:10592|MIM:608256|HPRD:09749
Chromosome:11
Location:11q23.3
Gene Description:sodium channel, voltage-gated, type IV, beta
Gene type:protein-coding
Gene Structure:
Genomic Context:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
399548CBCerebellum11.944593429565448.3643226623535
399548CTXCerebral cortex17.95398712158220.581033706665
399548HIPHippocampal region2.048275470733644.11696910858154
399548HPFHippocampal formation2.885289430618293.89475154876709
399548HYHypothalamus5.184949874877937.60215282440186
399548LSXLateral septal complex5.801766872406018.01824188232422
399548MBMidbrain19.262224197387733.5153541564941
399548MYMedulla28.39175224304250.0
399548OLFOlfactory bulb3.754438877105715.0365629196167
399548PPons28.725477218627950.0
399548PALPallidum14.241610527038624.1472034454346
399548RHPRetrohippocampal region3.945076704025273.7389988899231
399548sAMYStriatum-like amygdalar nuclei7.14196205139169.7018575668335
399548STRStriatum50.050.0
399548STRdStriatum dorsal region50.050.0
399548STRvStriatum ventral region50.050.0
399548THThalamus20.603065490722730.7902908325195
KARG Evidence 1
KARG ID:HOT0221
Entrez Gene ID:6330
RefSeq ID:NM_174934
Position Information:-, Enhancer, 87985bp
Linkage Marker:D11S976
Evidence Type:LINKAGE-BASED (SINGLE POINT)
Evidence Name:PUBMED
Evidence ID:9603607
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
6330GO:0001518IDAComponentvoltage-gated sodium channel complex
6330GO:0005248IDAFunctionvoltage-gated sodium channel activity
6330GO:0006811IEAProcession transport
6330GO:0006814IDAProcesssodium ion transport
6330GO:0007268ISSProcesssynaptic transmission
6330GO:0016020IEAComponentmembrane
6330GO:0016021IEAComponentintegral to membrane
6330GO:0031402IEAFunctionsodium ion binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
6330SCN4B_HUMANQ8IWT1IPR007110Ig-likeImmunoglobulin-like
6330SCN4B_HUMANQ8IWT1IPR013106V-setImmunoglobulin V-set

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