Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:6375
Official Symbol:XCL1
Other Aliases:ATAC|LPTN|LTN|SCM-1|SCM-1a|SCM1|SCYC1
See related:HGNC:10645|MIM:600250|HPRD:02595
Chromosome:1
Location:1q23
Gene Description:chemokine (C motif) ligand 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0858
ORGANISM:human
Entrez Gene ID:6375
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Upregulated
Fold Change:1.8 :: 1.6
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
16963CBCerebellum13.893592834472714.0309991836548
16963CTXCerebral cortex17.738052368164111.8083505630493
16963HIPHippocampal region14.447525978088413.1120910644531
16963HPFHippocampal formation19.304758071899415.9339952468872
16963HYHypothalamus14.610759735107410.1738624572754
16963LSXLateral septal complex5.189366817474373.31476712226868
16963MBMidbrain12.968687057495110.9674530029297
16963MYMedulla19.715980529785219.8556251525879
16963OLFOlfactory bulb29.368637084960922.9940490722656
16963PPons18.584102630615217.702974319458
16963PALPallidum8.210262298583985.97907781600952
16963RHPRetrohippocampal region30.128181457519521.8162727355957
16963sAMYStriatum-like amygdalar nuclei5.616524219512943.55054092407227
16963STRStriatum7.055897235870364.61540031433105
16963STRdStriatum dorsal region5.987867355346684.01532125473022
16963STRvStriatum ventral region12.72521495819097.64303827285767
16963THThalamus19.358695983886715.490044593811
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
6375GO:0005615IEAComponentextracellular space
6375GO:0006874TASProcesscalcium ion homeostasis
6375GO:0006935TASProcesschemotaxis
6375GO:0006955IEAProcessimmune response
6375GO:0007165TASProcesssignal transduction
6375GO:0007267TASProcesscell-cell signaling
6375GO:0008009TASFunctionchemokine activity
6375GO:0019735TASProcessantimicrobial humoral response (sensu Vertebrata)
6375GO:0050896IEAProcessresponse to stimulus
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_002986.16375NP_002986.1chemokine (C motif) ligand 1HPRD02595
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
6375XCL1_HUMANP47992IPR001811Chemokine_IL8Small chemokine, interleukin-8-like
6375XCL1_HUMANP47992IPR008105LymphotactinLymphotactin precursor

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