Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:6421
Official Symbol:SFPQ
Other Aliases:POMP100|PSF
See related:HGNC:10774|MIM:605199|HPRD:07284
Chromosome:1
Location:1p34.3
Gene Description:splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0333
ORGANISM:human
Entrez Gene ID:6421
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:71514
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
71514CBCerebellum100.0100.0
71514CTXCerebral cortex100.0100.0
71514HIPHippocampal region100.0100.0
71514HPFHippocampal formation100.0100.0
71514HYHypothalamus100.0100.0
71514LSXLateral septal complex100.0100.0
71514MBMidbrain100.0100.0
71514MYMedulla100.0100.0
71514OLFOlfactory bulb100.0100.0
71514PPons100.0100.0
71514PALPallidum100.0100.0
71514RHPRetrohippocampal region100.0100.0
71514sAMYStriatum-like amygdalar nuclei100.0100.0
71514STRStriatum100.0100.0
71514STRdStriatum dorsal region100.0100.0
71514STRvStriatum ventral region100.0100.0
71514THThalamus100.0100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
6421GO:0000166IEAFunctionnucleotide binding
6421GO:0000398IEAProcessnuclear mRNA splicing, via spliceosome
6421GO:0003677IEAFunctionDNA binding
6421GO:0003723IEAFunctionRNA binding
6421GO:0005515IPIFunctionprotein binding
6421GO:0005634IEAComponentnucleus
6421GO:0006281IEAProcessDNA repair
6421GO:0006310IEAProcessDNA recombination
6421GO:0006350IEAProcesstranscription
6421GO:0006355IEAProcessregulation of transcription, DNA-dependent
6421GO:0008380TASProcessRNA splicing
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_005057.1--RRP46HPRD07284
NP_005057.17150NP_003277.1DNA topoisomerase IHPRD07284
NP_005057.17150NP_003277.1DNA topoisomerase IHPRD00535
NP_005057.17150NP_003277.1DNA topoisomerase IBIND54914
NP_005057.156915NP_064543.3exosome component Rrp46HPRD16222
NP_005057.1140890NP_631907.1splicing factor, arginine/serine-rich 12HPRD18043
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
6421SFPQ_HUMANP23246IPR000893Luteo_ORF6Luteovirus ORF6 protein
6421SFPQ_HUMANP23246IPR006030Mollsc_rhodpsn_CMolluscan rhodopsin C-terminal tail
6421SFPQ_HUMANP23246IPR012975NOPSNOPS
6421SFPQ_HUMANP23246IPR003882Pistil_extensinPistil-specific extensin-like protein
6421SFPQ_HUMANP23246IPR000694PRO_richProline-rich region
6421SFPQ_HUMANP23246IPR000504RNP1_RNA_bdRNA-binding region RNP-1 (RNA recognition motif)

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