Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:64710
Official Symbol:NUCKS1
Other Aliases:FLJ21480|JC7|NUCKS
See related:HGNC:29923|HPRD:11406
Chromosome:1
Location:1q32.1
Gene Description:nuclear casein kinase and cyclin-dependent kinase substrate 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0050
ORGANISM:human
Entrez Gene ID:64710
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15009677
Addiction Drug:COCAINE
Addiction Drug Detail:COCAINE ABUSE
Addiction Brain Area:Nucleus Accumbens
Drug Effects:Downregulated
Fold Change:-0.39 :: -0.28 :: 0.08 :: -0.62 :: -0.28 :: -0.57 :: 0.17 :: -0.17 :: 0.97 :: -1.23
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
98415CBCerebellum37.09217071533265.8660202026367
98415CTXCerebral cortex100.0100.0
98415HIPHippocampal region100.0100.0
98415HPFHippocampal formation100.0100.0
98415HYHypothalamus84.573631286621186.809211730957
98415LSXLateral septal complex100.0100.0
98415MBMidbrain52.689353942871161.6490821838379
98415MYMedulla20.994653701782235.0038833618164
98415OLFOlfactory bulb99.2136383056641100.0
98415PPons34.847217559814551.726490020752
98415PALPallidum98.7012252807617100.0
98415RHPRetrohippocampal region100.0100.0
98415sAMYStriatum-like amygdalar nuclei100.0100.0
98415STRStriatum100.0100.0
98415STRdStriatum dorsal region100.0100.0
98415STRvStriatum ventral region100.0100.0
98415THThalamus100.0100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
64710GO:0005634IEAComponentnucleus
64710GO:0016301IEAFunctionkinase activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
64710NUCKS_HUMANQ9H1E3

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