Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:6507
Official Symbol:SLC1A3
Other Aliases:EA6|EAAT1|FLJ25094|GLAST|GLAST1
See related:HGNC:10941|MIM:600111|HPRD:02523
Chromosome:5
Location:5p13
Gene Description:solute carrier family 1 (glial high affinity glutamate transporter), member 3
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0447
ORGANISM:human
Entrez Gene ID:6507
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:29483
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
6507GO:0001504TASProcessneurotransmitter uptake
6507GO:0005313TASFunctionL-glutamate transporter activity
6507GO:0005624TASComponentmembrane fraction
6507GO:0006810IEAProcesstransport
6507GO:0006835IEAProcessdicarboxylic acid transport
6507GO:0007268TASProcesssynaptic transmission
6507GO:0015293IEAFunctionsymporter activity
6507GO:0015813TASProcessL-glutamate transport
6507GO:0016020IEAComponentmembrane
6507GO:0016021IEAComponentintegral to membrane
6507GO:0017153IEAFunctionsodium:dicarboxylate symporter activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
6507EAA1_HUMANP43003IPR001991Na/diCO_symportSodium:dicarboxylate symporter

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