Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:6563
Official Symbol:SLC14A1
Other Aliases:HUT11|HsT1341|JK|RACH1|UT-B1|UT1|UTE
See related:HGNC:10918|MIM:111000|HPRD:00195
Chromosome:18
Location:18q11-q12
Gene Description:solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0889
ORGANISM:human
Entrez Gene ID:6563
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Downregulated
Fold Change:-1.4 :: -1.9 :: 1 :: -1.1
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
108052CBCerebellum23.670845031738333.3661003112793
108052CTXCerebral cortex12.4567298889165.82668447494507
108052HIPHippocampal region3.629335641860962.7627227306366
108052HPFHippocampal formation3.000808238983152.28949904441833
108052HYHypothalamus10.43533992767333.93969488143921
108052LSXLateral septal complex11.40416812896733.58762192726135
108052MBMidbrain4.434317111968992.65032362937927
108052MYMedulla19.235792160034210.4849586486816
108052OLFOlfactory bulb21.399768829345711.411322593689
108052PPons11.07786941528324.87012052536011
108052PALPallidum8.562442779541023.09796929359436
108052RHPRetrohippocampal region1.799083471298221.54820418357849
108052sAMYStriatum-like amygdalar nuclei4.455723762512211.87890768051147
108052STRStriatum6.543256759643552.48623061180115
108052STRdStriatum dorsal region1.751223087310790.667753100395203
108052STRvStriatum ventral region24.61017608642589.07901954650879
108052THThalamus8.347656253.95235848426819
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
6563GO:0005886TASComponentplasma membrane
6563GO:0005887TASComponentintegral to plasma membrane
6563GO:0006810IEAProcesstransport
6563GO:0015204IEAFunctionurea transporter activity
6563GO:0015204TASFunctionurea transporter activity
6563GO:0015840IEAProcessurea transport
6563GO:0015840TASProcessurea transport
6563GO:0016021IEAComponentintegral to membrane
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
6563UT1_HUMANQ13336IPR002355Cu_oxidase_Cu_BSMulticopper oxidase, copper-binding site
6563UT1_HUMANQ13336IPR004937Urea_transporterUrea transporter

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