Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:6579
Official Symbol:SLCO1A2
Other Aliases:OATP|OATP-A|OATP1A2|SLC21A3
See related:HGNC:10956|MIM:602883|HPRD:09112
Chromosome:12
Location:12p12
Gene Description:solute carrier organic anion transporter family, member 1A2
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0476
ORGANISM:human
Entrez Gene ID:6579
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:170698
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
28248CBCerebellum0.1532004177570340.279875963926315
108096CBCerebellum5.84301312267788.25689980387688
28250CBCerebellum53.99921035766656.3038558959961
28248CTXCerebral cortex0.1047077104449270.135972067713737
108096CTXCerebral cortex1.117372125387191.68097653985023
28250CTXCerebral cortex30.624830245971719.6066188812256
28248HIPHippocampal region0.07446797937154770.148030981421471
108096HIPHippocampal region0.799565792083741.1817914173007
28250HIPHippocampal region24.315855026245121.9123783111572
28248HPFHippocampal formation0.07721903175115590.157024666666985
108096HPFHippocampal formation0.6661974973976610.924856200814247
28250HPFHippocampal formation24.131238937377919.7556018829346
108096HYHypothalamus0.3958170413970950.429679438471794
28248HYHypothalamus0.6962894797325130.719998598098755
28250HYHypothalamus25.238298416137718.5991325378418
28248LSXLateral septal complex0.02790467254817490.0
108096LSXLateral septal complex0.8997824564576150.79752392321825
28250LSXLateral septal complex16.463043212890611.8514842987061
28248MBMidbrain0.08513141423463820.173085749149323
108096MBMidbrain0.7992011606693271.3266711384058
28250MBMidbrain26.554336547851620.4626121520996
28248MYMedulla0.09026358276605610.125335782766342
108096MYMedulla1.798040002584462.09404850006104
28250MYMedulla41.112716674804730.7305355072021
28248OLFOlfactory bulb0.2355086207389830.234923988580704
108096OLFOlfactory bulb1.346937462687491.31454949826002
28250OLFOlfactory bulb42.485301971435532.955005645752
28248PPons0.232828527688980.410735815763474
108096PPons2.92777231335644.20174941420555
28250PPons34.071029663085924.9174823760986
28248PALPallidum0.08948735892772670.0658604875206947
108096PALPallidum0.3738232478499410.385613836348057
28250PALPallidum22.210287094116216.3074054718018
28248RHPRetrohippocampal region0.08690397441387180.178992405533791
108096RHPRetrohippocampal region0.499951571226120.636196743696928
28250RHPRetrohippocampal region23.32491493225116.2308082580566
28248sAMYStriatum-like amygdalar nuclei0.02436009608209130.0
108096sAMYStriatum-like amygdalar nuclei0.3616917356848720.291717156767845
28250sAMYStriatum-like amygdalar nuclei23.360582351684616.2681293487549
28248STRStriatum0.0415296554565430.0533853210508823
108096STRStriatum0.968429476022721.2306581735611
28250STRStriatum29.873992919921920.0023498535156
28248STRdStriatum dorsal region0.04125398024916650.0717240273952484
108096STRdStriatum dorsal region1.216932237148281.61872351169586
28250STRdStriatum dorsal region32.353412628173821.8904857635498
28248STRvStriatum ventral region0.04346621036529540.0374358892440796
108096STRvStriatum ventral region0.4412959292531010.608806904405355
28250STRvStriatum ventral region30.624444961547918.901309967041
28248THThalamus0.09332100301980970.0704998522996902
108096THThalamus0.3708877339959140.46875387430191
28250THThalamus25.471130371093819.227596282959
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
6579GO:0005215IEAFunctiontransporter activity
6579GO:0006811IEAProcession transport
6579GO:0008514TASFunctionorganic anion transporter activity
6579GO:0015711TASProcessorganic anion transport
6579GO:0016020IEAComponentmembrane
6579GO:0016021IEAComponentintegral to membrane
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
6579IPR007114MFSMajor facilitator superfamily
6579IPR011701MFS_1Major facilitator superfamily MFS_1
6579IPR004156OA_transporterOrganic anion transporter polypeptide OATP
6579IPR011497Prot_Inh_Kazal_2Protease inhibitor, Kazal-type
6579SO1A2_HUMANP46721IPR007114MFSMajor facilitator superfamily
6579SO1A2_HUMANP46721IPR011701MFS_1Major facilitator superfamily MFS_1
6579SO1A2_HUMANP46721IPR004156OA_transporterOrganic anion transporter polypeptide OATP
6579SO1A2_HUMANP46721IPR011497Prot_Inh_Kazal_2Protease inhibitor, Kazal-type

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