Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:6590
Official Symbol:SLPI
Other Aliases:ALK1|ALP|BLPI|HUSI|HUSI-I|MPI|WAP4|WFDC4
See related:HGNC:11092|MIM:107285|HPRD:00121
Chromosome:20
Location:20q12
Gene Description:secretory leukocyte peptidase inhibitor
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0283
ORGANISM:human
Entrez Gene ID:6590
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:20568
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
20568CBCerebellum4.218745231628424.98477268218994
20568CTXCerebral cortex8.486384391784673.49338459968567
20568HIPHippocampal region1.067119479179381.15841805934906
20568HPFHippocampal formation1.272555232048031.00473165512085
20568HYHypothalamus4.002258777618411.68956184387207
20568LSXLateral septal complex0.3930460512638090.157413676381111
20568MBMidbrain0.8865122795104980.863696038722992
20568MYMedulla5.868412494659426.77717733383179
20568OLFOlfactory bulb17.7694377899178.57988452911377
20568PPons1.197530865669250.841823816299438
20568PALPallidum5.499727725982671.67127001285553
20568RHPRetrohippocampal region1.618234276771550.844770491123199
20568sAMYStriatum-like amygdalar nuclei8.30225753784182.10093665122986
20568STRStriatum7.506548881530762.79057049751282
20568STRdStriatum dorsal region2.8362660408021.0124237537384
20568STRvStriatum ventral region27.445569992065410.1221103668213
20568THThalamus1.13540112972260.340469509363174
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
6590GO:0004867IEAFunctionserine-type endopeptidase inhibitor activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_003055.1--ScramblaseHPRD00121
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
6590ALK1_HUMANP03973IPR008197WAPWhey acidic protein, core region

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