Knowledgebase for Addiction-Related Genes
Home | Score | Chromosome | Pathway | Advanced Search | BLAST Search | Downloads | Publications | FAQ & Help |   

KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:6657
Official Symbol:SOX2
Other Aliases:ANOP3|MGC2413
See related:HGNC:11195|MIM:184429|HPRD:08921
Chromosome:3
Location:3q26.3-q27
Gene Description:SRY (sex determining region Y)-box 2
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0130
ORGANISM:human
Entrez Gene ID:6657
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:20674
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
20674CBCerebellum31.021873474121155.077693939209
20674CTXCerebral cortex66.094726562538.2307662963867
20674HIPHippocampal region34.072593688964825.6904220581055
20674HPFHippocampal formation38.831775665283224.257640838623
20674HYHypothalamus57.032352447509833.2768707275391
20674LSXLateral septal complex100.089.9731521606445
20674MBMidbrain28.267084121704118.5617847442627
20674MYMedulla26.870561599731416.7830142974854
20674OLFOlfactory bulb78.77112579345752.3309173583984
20674PPons32.295669555664119.8986682891846
20674PALPallidum56.881141662597738.8343963623047
20674RHPRetrohippocampal region45.285049438476621.670919418335
20674sAMYStriatum-like amygdalar nuclei87.587387084960948.8215942382812
20674STRStriatum50.557273864746130.3135585784912
20674STRdStriatum dorsal region27.703392028808615.1308965682983
20674STRvStriatum ventral region80.592712402343845.3044853210449
20674THThalamus48.861747741699228.1120109558105
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
6657GO:0003700NASFunctiontranscription factor activity
6657GO:0005634NASComponentnucleus
6657GO:0006325NASProcessestablishment and/or maintenance of chromatin architecture
6657GO:0006350IEAProcesstranscription
6657GO:0006355NASProcessregulation of transcription, DNA-dependent
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
6657SOX2_HUMANP48431IPR013558CTNNB1_bd_NCTNNB1 binding, N-teminal
6657SOX2_HUMANP48431IPR000135HMG_1/2High mobility group box HMG1 and HMG2
6657SOX2_HUMANP48431IPR000910HMG_1/2_boxHMG1/2 (high mobility group) box

© Center for Bioinformatics(CBI), Peking University
Any Comments and suggestions to : KARG GROUP.