Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:6695
Official Symbol:SPOCK1
Other Aliases:FLJ37170|SPOCK|TESTICAN|TIC1
See related:HGNC:11251|MIM:602264|HPRD:11887
Chromosome:5
Location:5q31
Gene Description:sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0345
ORGANISM:human
Entrez Gene ID:6695
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15816859
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Nucleus Accumbens
Drug Effects:Downregulated
Fold Change:-0.67
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
6695GO:0005509IEAFunctioncalcium ion binding
6695GO:0005578IEAComponentextracellular matrix (sensu Metazoa)
6695GO:0005615NRComponentextracellular space
6695GO:0006928TASProcesscell motility
6695GO:0007155TASProcesscell adhesion
6695GO:0007275TASProcessdevelopment
6695GO:0007399TASProcessnervous system development
6695GO:0008283TASProcesscell proliferation
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
6695TICN1_HUMANQ08629IPR013032EGF_like_regEGF-like region
6695TICN1_HUMANQ08629IPR002350Prot_inh_KazalProteinase inhibitor I1, Kazal
6695TICN1_HUMANQ08629IPR011497Prot_Inh_Kazal_2Protease inhibitor, Kazal-type
6695TICN1_HUMANQ08629IPR000716Thyroglobulin_1Thyroglobulin type-1

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