Knowledgebase for Addiction-Related Genes
Home | Score | Chromosome | Pathway | Advanced Search | BLAST Search | Downloads | Publications | FAQ & Help |   

KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:6853
Official Symbol:SYN1
Other Aliases:SYN1a|SYN1b|SYNI
See related:HGNC:11494|MIM:313440|HPRD:02433
Chromosome:X
Location:Xp11.23
Gene Description:synapsin I
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0516
ORGANISM:human
Entrez Gene ID:6853
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:24949
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
20964CBCerebellum82.7255249023438100.0
20964CTXCerebral cortex100.0100.0
20964HIPHippocampal region100.0100.0
20964HPFHippocampal formation100.0100.0
20964HYHypothalamus100.0100.0
20964LSXLateral septal complex100.0100.0
20964MBMidbrain100.0100.0
20964MYMedulla100.0100.0
20964OLFOlfactory bulb100.0100.0
20964PPons100.0100.0
20964PALPallidum100.0100.0
20964RHPRetrohippocampal region100.0100.0
20964sAMYStriatum-like amygdalar nuclei100.0100.0
20964STRStriatum100.0100.0
20964STRdStriatum dorsal region100.0100.0
20964STRvStriatum ventral region100.0100.0
20964THThalamus100.0100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
6853GO:0003779IEAFunctionactin binding
6853GO:0005215TASFunctiontransporter activity
6853GO:0007268TASProcesssynaptic transmission
6853GO:0007269IEAProcessneurotransmitter secretion
6853GO:0008021IEAComponentsynaptic vesicle
6853GO:0045202IEAComponentsynapse
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-8224NP_003481.2synapsin III isoform IIIaHPRD04083
-9722NP_055512.1nitric oxide synthase 1 (neuronal) adaptor proteinHPRD12023
-6854NP_598328.1synapsin II isoform IIaHPRD02857
NP_008881.2--PHOXHPRD02433
NP_008881.2--Phospholipase C-gammaHPRD02433
NP_008881.26854-Synapsin IIHPRD02433
NP_008881.28224-Synapsin IIIHPRD02433
NP_008881.29722-CAPONHPRD02433
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
6853IPR006030Mollsc_rhodpsn_CMolluscan rhodopsin C-terminal tail
6853IPR000694PRO_richProline-rich region
6853IPR001359SynapsinSynapsin
6853IPR003993treacleTreacher Collins syndrome protein Treacle
6853SYN1_HUMANP17600IPR006030Mollsc_rhodpsn_CMolluscan rhodopsin C-terminal tail
6853SYN1_HUMANP17600IPR000694PRO_richProline-rich region
6853SYN1_HUMANP17600IPR001359SynapsinSynapsin

© Center for Bioinformatics(CBI), Peking University
Any Comments and suggestions to : KARG GROUP.