Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:6855
Official Symbol:SYP
Other Aliases:-
See related:HGNC:11506|MIM:313475|HPRD:02435
Chromosome:X
Location:Xp11.23-p11.22
Gene Description:synaptophysin
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0454
ORGANISM:human
Entrez Gene ID:6855
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:24804
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
20977CBCerebellum100.0100.0
20977CTXCerebral cortex100.0100.0
20977HIPHippocampal region100.0100.0
20977HPFHippocampal formation100.0100.0
20977HYHypothalamus100.0100.0
20977LSXLateral septal complex100.0100.0
20977MBMidbrain100.0100.0
20977MYMedulla100.0100.0
20977OLFOlfactory bulb100.0100.0
20977PPons100.0100.0
20977PALPallidum100.0100.0
20977RHPRetrohippocampal region100.0100.0
20977sAMYStriatum-like amygdalar nuclei100.0100.0
20977STRStriatum100.0100.0
20977STRdStriatum dorsal region100.0100.0
20977STRvStriatum ventral region100.0100.0
20977THThalamus100.0100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
6855GO:0005215IEAFunctiontransporter activity
6855GO:0005509NASFunctioncalcium ion binding
6855GO:0005515NASFunctionprotein binding
6855GO:0006810IEAProcesstransport
6855GO:0008021IEAComponentsynaptic vesicle
6855GO:0015485IDAFunctioncholesterol binding
6855GO:0016020IEAComponentmembrane
6855GO:0016188NASProcesssynaptic vesicle maturation
6855GO:0019717IEAComponentsynaptosome
6855GO:0030285NASComponentintegral to synaptic vesicle membrane
6855GO:0045202IEAComponentsynapse
6855GO:0048499NASProcesssynaptic vesicle membrane organization and biogenesis
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_003170.1--SynaptobrevinHPRD02435
NP_003170.1--Gamma adaptinHPRD02435
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
6855SYPH_HUMANP08247IPR002952EggshellEggshell protein
6855SYPH_HUMANP08247IPR008253MarvelMarvel
6855SYPH_HUMANP08247IPR001285SynaptophysinSynaptophysin/synaptoporin

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