Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:6860
Official Symbol:SYT4
Other Aliases:HsT1192|KIAA1342
See related:HGNC:11512|MIM:600103|HPRD:02519
Chromosome:18
Location:18q12.3
Gene Description:synaptotagmin IV
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0371
ORGANISM:human
Entrez Gene ID:6860
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:64440
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
20983CBCerebellum0.5469294786453250.774462878704071
20983CTXCerebral cortex1.263179540634161.50851082801819
20983HIPHippocampal region0.6412375569343570.804902970790863
20983HPFHippocampal formation0.8821802139282231.00378525257111
20983HYHypothalamus2.248171806335452.58528017997742
20983LSXLateral septal complex0.06028052419424060.0583224967122078
20983MBMidbrain1.03028261661531.1875239610672
20983MYMedulla2.962137460708624.97353410720825
20983OLFOlfactory bulb0.8125731945037840.803437650203705
20983PPons1.382296562194822.1124324798584
20983PALPallidum0.8642420172691351.06848645210266
20983RHPRetrohippocampal region1.261923432350161.23214268684387
20983sAMYStriatum-like amygdalar nuclei1.40208935737611.71823441982269
20983STRStriatum0.2576183378696440.302522569894791
20983STRdStriatum dorsal region0.08617376536130910.0997168943285942
20983STRvStriatum ventral region0.09767837077379230.0851797312498093
20983THThalamus0.9284942150115970.922842621803284
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
6860GO:0005215IEAFunctiontransporter activity
6860GO:0005509IEAFunctioncalcium ion binding
6860GO:0006810IEAProcesstransport
6860GO:0008021IEAComponentsynaptic vesicle
6860GO:0016020IEAComponentmembrane
6860GO:0016021ISSComponentintegral to membrane
6860GO:0017158ISSProcessregulation of calcium ion-dependent exocytosis
6860GO:0045202IEAComponentsynapse
6860GO:0048489ISSProcesssynaptic vesicle transport
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-7021NP_003212.1transcription factor AP-2 beta (activating enhancer binding protein 2 beta)HPRD03360
-9378NP_004792.1neurexin 1 isoform alpha precursorHPRD11858
-10492NP_006363.3synaptotagmin binding, cytoplasmic RNA interacting proteinHPRD06734
NP_065834.1--Syntaxin 2HPRD02519
NP_065834.1--Syntaxin 3HPRD02519
NP_065834.17021-Transcription factor AP-2 betaHPRD02519
NP_065834.110492-NS1 associated protein 1HPRD02519
NP_065834.16860NP_065834.1synaptotagmin IVHPRD02519
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
6860SYT4_HUMANQ9H2B2IPR002149Alatroxin_rcptA-latrotoxin receptor interaction
6860SYT4_HUMANQ9H2B2IPR000008C2C2
6860SYT4_HUMANQ9H2B2IPR013583PRT_C_plnPhosphoribosyltransferase C-terminal, plant
6860SYT4_HUMANQ9H2B2IPR001565SynaptotagminSynaptotagmin

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