Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:6866
Official Symbol:TAC3
Other Aliases:NKB|NKNB|PRO1155|ZNEUROK1
See related:HGNC:11521|MIM:162330|HPRD:08877
Chromosome:12
Location:12q13-q21
Gene Description:tachykinin 3 (neuromedin K, neurokinin beta)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0337
ORGANISM:human
Entrez Gene ID:6866
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:21334
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
21334CBCerebellum0.6805019378662111.37355053424835
21334CTXCerebral cortex4.066231250762944.45815324783325
21334HIPHippocampal region3.982625961303718.02152824401855
21334HPFHippocampal formation3.412106037139895.70650959014893
21334HYHypothalamus10.272118568420413.2539205551147
21334LSXLateral septal complex1.883214473724372.01691460609436
21334MBMidbrain2.034411668777472.66691613197327
21334MYMedulla1.462383508682251.52002990245819
21334OLFOlfactory bulb6.206853866577155.14681386947632
21334PPons1.012945413589480.801741600036621
21334PALPallidum7.3667564392089812.1159706115723
21334RHPRetrohippocampal region2.552537441253662.89165806770325
21334sAMYStriatum-like amygdalar nuclei7.5147728919982912.8812246322632
21334STRStriatum2.549403667449953.0751838684082
21334STRdStriatum dorsal region0.8918384313583371.42765784263611
21334STRvStriatum ventral region4.831965446472173.2828962802887
21334THThalamus2.137701749801643.42099356651306
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
6866GO:0005102TASFunctionreceptor binding
6866GO:0005615TASComponentextracellular space
6866GO:0005625TASComponentsoluble fraction
6866GO:0007217TASProcesstachykinin signaling pathway
6866GO:0007218IEAProcessneuropeptide signaling pathway
6866GO:0007565TASProcesspregnancy
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-6870NP_001050.1tachykinin receptor 3HPRD01209
NP_037383.16870-Tachykinin receptor 3HPRD08877
NP_037383.16869NP_001049.1tachykinin receptor 1 isoform longHPRD08877
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
6866IPR003635NeurokininNeurokinin
6866IPR013055Tachy_Neuro_lkeTachykinin/Neurokinin like
6866TKNK_HUMANQ9UHF0IPR003635NeurokininNeurokinin
6866TKNK_HUMANQ9UHF0IPR013055Tachy_Neuro_lkeTachykinin/Neurokinin like

© Center for Bioinformatics(CBI), Peking University
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