Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:6879
Official Symbol:TAF7
Other Aliases:TAF2F|TAFII55
See related:HGNC:11541|MIM:600573|HPRD:07196
Chromosome:5
Location:5q31
Gene Description:TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0878
ORGANISM:human
Entrez Gene ID:6879
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Upregulated
Fold Change:1.4 :: 1.4 :: 1.1 :: 1.1
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
24074CBCerebellum15.12789344787617.0943241119385
24074CTXCerebral cortex20.269945144653314.7528219223022
24074HIPHippocampal region12.853050231933612.7361927032471
24074HPFHippocampal formation15.068430900573712.9785213470459
24074HYHypothalamus15.586730003356912.4544954299927
24074LSXLateral septal complex6.132002830505373.94276928901672
24074MBMidbrain20.165639877319317.8135185241699
24074MYMedulla31.929143905639635.2837028503418
24074OLFOlfactory bulb21.322259902954116.8112468719482
24074PPons24.568069458007826.1008739471436
24074PALPallidum19.418973922729517.8985118865967
24074RHPRetrohippocampal region18.903264999389613.5340938568115
24074sAMYStriatum-like amygdalar nuclei18.150142669677712.8984422683716
24074STRStriatum8.275621414184576.218421459198
24074STRdStriatum dorsal region7.149713039398195.64586400985718
24074STRvStriatum ventral region8.408076286315925.80922412872314
24074THThalamus16.089372634887713.9391040802002
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
6879GO:0003700IEAFunctiontranscription factor activity
6879GO:0003713TASFunctiontranscription coactivator activity
6879GO:0005515TASFunctionprotein binding
6879GO:0005634IEAComponentnucleus
6879GO:0005669IDAComponenttranscription factor TFIID complex
6879GO:0006355IEAProcessregulation of transcription, DNA-dependent
6879GO:0016251TASFunctiongeneral RNA polymerase II transcription factor activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-8805NP_056989.2transcriptional intermediary factor 1 alpha isoform aHPRD04556
NP_005633.2--TAFII230HPRD07196
NP_005633.28805-Transcriptional intermediary factor 1, alphaHPRD07196
NP_005633.229894NP_037423.1cleavage and polyadenylation specific factor 1, 160kDaHPRD07196
NP_005633.229894NP_037423.1cleavage and polyadenylation specific factor 1, 160kDaHPRD05823
NP_005633.28148NP_631961.1TBP-associated factor 15 isoform 1HPRD09031
NP_005633.2155871NP_057853.1Tat--
NP_005633.2155871NP_057853.1Tat--
NP_005633.2155871NP_057853.1Tat--
NP_005633.2155871NP_057853.1Tat--
NP_005633.2155871NP_057853.1Tat--
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
6879TAF7_HUMANQ15545IPR006751TAFII55_NTAFII55 protein conserved region

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