Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:7001
Official Symbol:PRDX2
Other Aliases:MGC4104|NKEFB|PRP|PRXII|TDPX1|TSA
See related:HGNC:9353|MIM:600538|HPRD:02763
Chromosome:19
Location:19p13.2
Gene Description:peroxiredoxin 2
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0561
ORGANISM:human
Entrez Gene ID:7001
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:29338
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 2
KARG ID:EVIP0194
ORGANISM:human
Entrez Gene ID:7001
Evidence Type:Proteomics
Evidence ID Type:PUBMED
Evidence ID:15542695
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Whole Brain
Drug Effects:Upregulated
Fold Change:5.20
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
7001GO:0004601IEAFunctionperoxidase activity
7001GO:0005737TASComponentcytoplasm
7001GO:0006916TASProcessanti-apoptosis
7001GO:0006979IMPProcessresponse to oxidative stress
7001GO:0006979NASProcessresponse to oxidative stress
7001GO:0008379TASFunctionthioredoxin peroxidase activity
7001GO:0016491IEAFunctionoxidoreductase activity
7001GO:0042981IMPProcessregulation of apoptosis
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
7001IPR000866AhpC-TSAAlkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen
7001PRDX2_HUMANP32119IPR000866AhpC-TSAAlkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen
7001PRDX2_HUMANP32119IPR013740RedoxinRedoxin

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