Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:7070
Official Symbol:THY1
Other Aliases:CD90
See related:HGNC:11801|MIM:188230|HPRD:01769
Chromosome:11
Location:11q22.3-q23
Gene Description:Thy-1 cell surface antigen
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0074
ORGANISM:human
Entrez Gene ID:7070
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:21838
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 2
KARG ID:QTL0133
ORGANISM:human
Entrez Gene ID:7070
Evidence Type:QTL assay
Evidence ID Type:PUBMED
Evidence ID:NA
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
21838CBCerebellum99.2870712280273100.0
21838CTXCerebral cortex100.0100.0
21838HIPHippocampal region100.0100.0
21838HPFHippocampal formation100.0100.0
21838HYHypothalamus100.0100.0
21838LSXLateral septal complex100.0100.0
21838MBMidbrain100.0100.0
21838MYMedulla100.0100.0
21838OLFOlfactory bulb100.0100.0
21838PPons100.0100.0
21838PALPallidum100.0100.0
21838RHPRetrohippocampal region100.0100.0
21838sAMYStriatum-like amygdalar nuclei100.0100.0
21838STRStriatum100.0100.0
21838STRdStriatum dorsal region100.0100.0
21838STRvStriatum ventral region100.0100.0
21838THThalamus100.0100.0
KARG Evidence 3
KARG ID:QTL0133
Trait:alcohol preference
Peak:26
Peak Marker:D9Mit330
Parents:(C57BL/6J x DBA/2J)F2 intercross
Evidence ID:9726281
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
7070GO:0000004NDProcessbiological process unknown
7070GO:0001525ISSProcessangiogenesis
7070GO:0005100ISSFunctionRho GTPase activator activity
7070GO:0005178IPIFunctionintegrin binding
7070GO:0005515IPIFunctionprotein binding
7070GO:0005554NDFunctionmolecular function unknown
7070GO:0005829ISSComponentcytosol
7070GO:0005887TASComponentintegral to plasma membrane
7070GO:0006469ISSProcessnegative regulation of protein kinase activity
7070GO:0007010ISSProcesscytoskeleton organization and biogenesis
7070GO:0008372NDComponentcellular component unknown
7070GO:0009897ISSComponentexternal side of plasma membrane
7070GO:0016337ISSProcesscell-cell adhesion
7070GO:0030336ISSProcessnegative regulation of cell migration
7070GO:0030426ISSComponentgrowth cone
7070GO:0043066ISSProcessnegative regulation of apoptosis
7070GO:0043547ISSProcesspositive regulation of GTPase activity
7070GO:0045121NASComponentlipid raft
7070GO:0045576ISSProcessmast cell activation
7070GO:0046549ISSProcessretinal cone cell development
7070GO:0048041ISSProcessfocal adhesion formation
7070GO:0048147ISSProcessnegative regulation of fibroblast proliferation
7070GO:0048503ISSFunctionGPI anchor binding
7070GO:0050731ISSProcesspositive regulation of peptidyl-tyrosine phosphorylation
7070GO:0050771ISSProcessnegative regulation of axonogenesis
7070GO:0050852ISSProcessT cell receptor signaling pathway
7070GO:0050860ISSProcessnegative regulation of T cell receptor signaling pathway
7070GO:0050870ISSProcesspositive regulation of T cell activation
7070GO:0051281ISSProcesspositive regulation of release of sequestered calcium ion into cytosol
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_006279.2--Thy-1 binding proteinHPRD01769
NP_006279.2---BIND314244
NP_006279.27070NP_006279.2Thy-1 cell surface antigenHPRD01769
NP_006279.2155030NP_579876.2matrix--
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
7070THY1_HUMANP04216IPR007110Ig-likeImmunoglobulin-like
7070THY1_HUMANP04216IPR013151ImmunoglobulinImmunoglobulin

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