Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:7071
Official Symbol:KLF10
Other Aliases:EGRA|TIEG|TIEG1
See related:HGNC:11810|MIM:601878|HPRD:03527
Chromosome:8
Location:8q22.2
Gene Description:Kruppel-like factor 10
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0362
ORGANISM:human
Entrez Gene ID:7071
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:21847
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 2
KARG ID:EVIC0613
ORGANISM:human
Entrez Gene ID:7071
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:81813
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
21847CBCerebellum2.06534010171892.29789578914642
21847CTXCerebral cortex95.487136840820383.2745513916016
21847HIPHippocampal region25.112926483154343.6152744293213
21847HPFHippocampal formation27.287151336669937.0412921905518
21847HYHypothalamus1.074006345123050.868470281362534
21847LSXLateral septal complex5.101552963256844.53075623512268
21847MBMidbrain1.475380957126621.60761988162994
21847MYMedulla1.40011000633241.72484707832336
21847OLFOlfactory bulb45.323965072631839.9045543670654
21847PPons1.179412305355071.37996798753738
21847PALPallidum1.069954961538310.825553089380264
21847RHPRetrohippocampal region29.867052078247128.6432104110718
21847sAMYStriatum-like amygdalar nuclei14.813771724700913.9300775527954
21847STRStriatum12.2313790321359.32336759567261
21847STRdStriatum dorsal region12.88735532760629.58091998100281
21847STRvStriatum ventral region10.87569904327396.92817950248718
21847THThalamus1.694050192832951.85122472047806
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
7071GO:0000122TASProcessnegative regulation of transcription from RNA polymerase II promoter
7071GO:0001501TASProcessskeletal development
7071GO:0003676IEAFunctionnucleic acid binding
7071GO:0003700TASFunctiontranscription factor activity
7071GO:0005634IEAComponentnucleus
7071GO:0005634TASComponentnucleus
7071GO:0006350IEAProcesstranscription
7071GO:0006355IEAProcessregulation of transcription, DNA-dependent
7071GO:0007179TASProcesstransforming growth factor beta receptor signaling pathway
7071GO:0007267TASProcesscell-cell signaling
7071GO:0008270IEAFunctionzinc ion binding
7071GO:0008283TASProcesscell proliferation
7071GO:0008285TASProcessnegative regulation of cell proliferation
7071GO:0046872IEAFunctionmetal ion binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
7071KLF10_HUMANQ13118IPR000694PRO_richProline-rich region
7071KLF10_HUMANQ13118IPR007087Znf_C2H2Zinc finger, C2H2-type

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