Knowledgebase for Addiction-Related Genes
Home | Score | Chromosome | Pathway | Advanced Search | BLAST Search | Downloads | Publications | FAQ & Help |   

KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:7276
Official Symbol:TTR
Other Aliases:HsT2651|PALB|TBPA
See related:HGNC:12405|MIM:176300|HPRD:01447
Chromosome:18
Location:18q12.1
Gene Description:transthyretin (prealbumin, amyloidosis type I)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0181
ORGANISM:human
Entrez Gene ID:7276
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:22139
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
22139CBCerebellum14.220136642456124.9701480865479
76974CBCerebellum3.994495153427124.34542226791382
76974CTXCerebral cortex5.81956291198733.81013035774231
22139CTXCerebral cortex7.541204452514658.02916622161865
76974HIPHippocampal region3.70633196830753.41954708099365
22139HIPHippocampal region8.5640459060668913.0394430160522
76974HPFHippocampal formation3.96002483367923.48001551628113
22139HPFHippocampal formation6.036438941955578.39729022979736
22139HYHypothalamus0.4095627367496490.791526436805725
76974HYHypothalamus7.737684726715096.60300588607788
76974LSXLateral septal complex2.173620223999021.41980493068695
22139LSXLateral septal complex5.346083164215097.609459400177
22139MBMidbrain0.7893720269203191.49102187156677
76974MBMidbrain5.045162200927735.19360208511353
76974MYMedulla13.810770988464413.9446935653687
22139MYMedulla19.578863143920929.9655323028564
22139OLFOlfactory bulb1.349486827850342.47931265830994
76974OLFOlfactory bulb11.5145339965829.62924575805664
22139PPons1.045125126838681.59068620204926
76974PPons10.339164733886712.4314584732056
22139PALPallidum0.1286565512418750.256913244724274
76974PALPallidum4.033802509307863.34228563308716
22139RHPRetrohippocampal region1.090402960777281.02040588855743
76974RHPRetrohippocampal region4.189723968505863.18937706947327
22139sAMYStriatum-like amygdalar nuclei2.271260976791382.42284250259399
76974sAMYStriatum-like amygdalar nuclei8.587827682495125.18375158309937
76974STRStriatum3.495820045471192.49792504310608
22139STRStriatum5.147018909454356.8061957359314
76974STRdStriatum dorsal region2.658185005187991.87495481967926
22139STRdStriatum dorsal region7.036622047424329.52990245819092
22139STRvStriatum ventral region0.06113193556666370.0872968882322311
76974STRvStriatum ventral region5.297198295593264.32407283782959
22139THThalamus18.610269546508827.2235012054443
76974THThalamus3.809190988540652.63895392417908
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
7276GO:0005179IEAFunctionhormone activity
7276GO:0005386IEAFunctioncarrier activity
7276GO:0005496IEAFunctionsteroid binding
7276GO:0005576NASComponentextracellular region
7276GO:0006590IEAProcessthyroid hormone generation
7276GO:0006810NASProcesstransport
7276GO:0015349NRFunctionthyroid hormone transporter activity
7276GO:0016918IEAFunctionretinal binding
7276GO:0019841IEAFunctionretinol binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_000362.1---BIND196630
NP_000362.1---BIND196641
NP_000362.1---BIND196638
NP_000362.1---BIND196775
NP_000362.1---BIND196637
NP_000362.1---BIND196636
NP_000362.1---BIND196635
NP_000362.1---BIND196774
NP_000362.1---BIND196773
NP_000362.1---BIND196772
NP_000362.1---BIND196634
NP_000362.1---BIND196633
NP_000362.1---BIND196632
NP_000362.1---BIND196631
NP_000362.1---BIND196639
NP_000362.1---BIND196640
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
7276TTHY_HUMANP02766IPR000895TransthyretinTransthyretin

© Center for Bioinformatics(CBI), Peking University
Any Comments and suggestions to : KARG GROUP.