Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:7336
Official Symbol:UBE2V2
Other Aliases:DDVIT1|DDVit-1|EDAF-1|EDPF-1|EDPF1|MMS2|UEV-2|UEV2
See related:HGNC:12495|MIM:603001|HPRD:04300
Chromosome:8
Location:8q11.21
Gene Description:ubiquitin-conjugating enzyme E2 variant 2
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0252
ORGANISM:human
Entrez Gene ID:7336
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:70620
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 2
KARG ID:EVIM0315
ORGANISM:human
Entrez Gene ID:7336
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15816859
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Nucleus Accumbens
Drug Effects:Downregulated
Fold Change:-0.60
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
70620CBCerebellum5.173991680145265.7519326210022
70620CTXCerebral cortex2.393101215362551.82002902030945
70620HIPHippocampal region4.733415126800544.21121454238892
70620HPFHippocampal formation4.021012783050543.26782917976379
70620HYHypothalamus2.74016594886782.11227583885193
70620LSXLateral septal complex0.8850353956222530.806607782840729
70620MBMidbrain4.052605152130133.79862952232361
70620MYMedulla9.5163335800170911.5904092788696
70620OLFOlfactory bulb2.613727092742921.7709287405014
70620PPons6.573389053344737.43466234207153
70620PALPallidum1.91828477382661.57075536251068
70620RHPRetrohippocampal region2.338593482971191.54101455211639
70620sAMYStriatum-like amygdalar nuclei0.6409747600555420.492634177207947
70620STRStriatum0.6206417679786680.465552389621735
70620STRdStriatum dorsal region0.5277151465415950.37493759393692
70620STRvStriatum ventral region0.8432075381278990.618803203105927
70620THThalamus2.18566322326661.6102557182312
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
7336GO:0000074TASProcessregulation of progression through cell cycle
7336GO:0000209TASProcessprotein polyubiquitination
7336GO:0004840TASFunctionubiquitin conjugating enzyme activity
7336GO:0004842IEAFunctionubiquitin-protein ligase activity
7336GO:0006282TASProcessregulation of DNA repair
7336GO:0006512IEAProcessubiquitin cycle
7336GO:0008283TASProcesscell proliferation
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_003341.18915NP_003912.1B-cell CLL/lymphoma 10BIND55263
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
7336UB2V2_HUMANQ15819IPR000608UBQ-conjugat_E2Ubiquitin-conjugating enzyme, E2

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