Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:7342
Official Symbol:UBP1
Other Aliases:DKFZp686L1745|LBP-1B|LBP-1a|LBP1A|LBP1B
See related:HGNC:12507|MIM:609784|HPRD:10291
Chromosome:3
Location:3p22.3
Gene Description:upstream binding protein 1 (LBP-1a)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0247
ORGANISM:human
Entrez Gene ID:7342
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15816859
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Prefrontal Cortex
Drug Effects:Downregulated
Fold Change:-0.56
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
22221CBCerebellum52.709712982177759.3437271118164
22221CTXCerebral cortex100.0100.0
22221HIPHippocampal region100.0100.0
22221HPFHippocampal formation100.0100.0
22221HYHypothalamus88.382835388183672.8474502563477
22221LSXLateral septal complex91.603904724121172.3201370239258
22221MBMidbrain88.906501770019579.8347396850586
22221MYMedulla57.05652618408255.8373260498047
22221OLFOlfactory bulb100.0100.0
22221PPons69.069335937565.0440444946289
22221PALPallidum92.272697448730582.6022644042969
22221RHPRetrohippocampal region100.098.7290115356445
22221sAMYStriatum-like amygdalar nuclei100.097.4106674194336
22221STRStriatum100.0100.0
22221STRdStriatum dorsal region100.0100.0
22221STRvStriatum ventral region100.0100.0
22221THThalamus100.0100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
7342GO:0003700TASFunctiontranscription factor activity
7342GO:0003714TASFunctiontranscription corepressor activity
7342GO:0005634TASComponentnucleus
7342GO:0006357TASProcessregulation of transcription from RNA polymerase II promoter
7342GO:0016481TASProcessnegative regulation of transcription
7342GO:0016566TASFunctionspecific transcriptional repressor activity
7342GO:0019079TASProcessviral genome replication
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_055332.229842NP_055368.1LBP-9HPRD18175
NP_055332.229842NP_055368.1LBP-9HPRD10291
NP_055332.2155871NP_057853.1Tat--
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
7342IPR007604CP2CP2 transcription factor
7342IPR001660SAMSterile alpha motif SAM

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