Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:7343
Official Symbol:UBTF
Other Aliases:NOR-90|UBF
See related:HGNC:12511|MIM:600673|HPRD:02814
Chromosome:17
Location:17q21.3
Gene Description:upstream binding transcription factor, RNA polymerase I
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0483
ORGANISM:human
Entrez Gene ID:7343
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:25574
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
21429CBCerebellum100.0100.0
21429CTXCerebral cortex100.0100.0
21429HIPHippocampal region100.0100.0
21429HPFHippocampal formation100.0100.0
21429HYHypothalamus100.0100.0
21429LSXLateral septal complex100.0100.0
21429MBMidbrain100.0100.0
21429MYMedulla99.8853378295898100.0
21429OLFOlfactory bulb100.0100.0
21429PPons94.5492858886719100.0
21429PALPallidum100.0100.0
21429RHPRetrohippocampal region100.0100.0
21429sAMYStriatum-like amygdalar nuclei100.0100.0
21429STRStriatum100.0100.0
21429STRdStriatum dorsal region100.0100.0
21429STRvStriatum ventral region100.0100.0
21429THThalamus100.0100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
7343GO:0003677IEAFunctionDNA binding
7343GO:0003701TASFunctionRNA polymerase I transcription factor activity
7343GO:0005634IEAComponentnucleus
7343GO:0005730TASComponentnucleolus
7343GO:0006350IEAProcesstranscription
7343GO:0006355IEAProcessregulation of transcription, DNA-dependent
7343GO:0006356TASProcessregulation of transcription from RNA polymerase I promoter
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-8660NP_003740.2insulin receptor substrate 2HPRD02878
-64425NP_071935.1RNA polymerase I associated factor 53HPRD15096
-64425NP_071935.1RNA polymerase I associated factor 53HPRD15096
NP_055048.1--p204HPRD02814
NP_055048.1--RPA53HPRD02814
NP_055048.18660-IRS2HPRD02814
NP_055048.110849NP_036231.1CD3E antigen, epsilon polypeptide associated proteinHPRD02814
NP_055048.110849NP_036231.1CD3E antigen, epsilon polypeptide associated proteinHPRD00125
NP_055048.151176NP_057353.1lymphoid enhancer binding factor-1HPRD02814
NP_055048.151176NP_057353.1lymphoid enhancer binding factor-1HPRD01075
NP_055048.1125168U13369.1Human ribosomal DNA complete repeating unit.BIND197249
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
7343UBF1_HUMANP17480IPR013558CTNNB1_bd_NCTNNB1 binding, N-teminal
7343UBF1_HUMANP17480IPR000135HMG_1/2High mobility group box HMG1 and HMG2
7343UBF1_HUMANP17480IPR000910HMG_1/2_boxHMG1/2 (high mobility group) box
7343UBF1_HUMANP17480IPR002038OsteopontinOsteopontin

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