Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:7386
Official Symbol:UQCRFS1
Other Aliases:RIS1
See related:HGNC:12587|MIM:191327|HPRD:01874
Chromosome:19
Location:19q12-q13.1
Gene Description:ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0554
ORGANISM:human
Entrez Gene ID:7386
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:291103
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
66694CBCerebellum48.1273097991943100.0
66694CTXCerebral cortex100.0100.0
66694HIPHippocampal region100.0100.0
66694HPFHippocampal formation96.6570205688477100.0
66694HYHypothalamus80.367134094238386.8242263793945
66694LSXLateral septal complex91.165264129638785.2617301940918
66694MBMidbrain86.222148895263798.2878761291504
66694MYMedulla83.0616874694824100.0
66694OLFOlfactory bulb98.0779418945312100.0
66694PPons82.9201469421387100.0
66694PALPallidum92.3980827331543100.0
66694RHPRetrohippocampal region92.8013114929199100.0
66694sAMYStriatum-like amygdalar nuclei80.971437454223681.1699314117432
66694STRStriatum87.395416259765680.7687606811523
66694STRdStriatum dorsal region89.929191589355582.4853248596191
66694STRvStriatum ventral region82.104839324951273.8669338226318
66694THThalamus99.5148658752441100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
7386GO:0005506IEAFunctioniron ion binding
7386GO:0005739IEAComponentmitochondrion
7386GO:0005750NASComponentrespiratory chain complex III (sensu Eukaryota)
7386GO:0006118NASProcesselectron transport
7386GO:0008121NASFunctionubiquinol-cytochrome-c reductase activity
7386GO:0016020IEAComponentmembrane
7386GO:0016021IEAComponentintegral to membrane
7386GO:0016491IEAFunctionoxidoreductase activity
7386GO:0046872IEAFunctionmetal ion binding
7386GO:0051537IEAFunction2 iron, 2 sulfur cluster binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
7386UCRI_HUMANP47985IPR013626PaOPheophorbide a oxygenase
7386UCRI_HUMANP47985IPR005805RieskeRieske iron-sulfur protein
7386UCRI_HUMANP47985IPR005806Rieske_regRieske [2Fe-2S] region
7386UCRI_HUMANP47985IPR004192UCR_TM_regionUbiquinol cytochrome reductase transmembrane region

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