Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:7593
Official Symbol:ZNF42
Other Aliases:MZF-1|MZF1|MZF1B|ZSCAN6
See related:HGNC:13108|MIM:194550|HPRD:01930
Chromosome:19
Location:19q13.2-q13.4
Gene Description:zinc finger protein 42 (myeloid-specific retinoic acid-responsive)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0235
ORGANISM:human
Entrez Gene ID:7593
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11093800
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ADMINISTRATION
Addiction Brain Area:SH-SY5Y neuroblastoma cells
Drug Effects:Downregulated
Fold Change:At least 2-folds difference
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
109889CBCerebellum0.7936719059944151.7048647403717
109889CTXCerebral cortex0.1712278574705120.252168506383896
109889HIPHippocampal region0.1019459962844850.242359563708305
109889HPFHippocampal formation0.0968589484691620.211650058627129
109889HYHypothalamus0.07033892720937730.201612249016762
109889LSXLateral septal complex0.1198559105396270.104052573442459
109889MBMidbrain0.1057529374957080.289905160665512
109889MYMedulla0.403660684823990.528893887996674
109889OLFOlfactory bulb0.5253197550773621.25607538223267
109889PPons0.120823897421360.303679019212723
109889PALPallidum0.05431894958019260.0967530533671379
109889RHPRetrohippocampal region0.06327551603317260.149799272418022
109889sAMYStriatum-like amygdalar nuclei0.1858125329017640.0906567722558975
109889STRStriatum0.08853711932897570.112345486879349
109889STRdStriatum dorsal region0.08498898148536680.149302497506142
109889STRvStriatum ventral region0.05208892002701760.0335510186851025
109889THThalamus0.2423390001058580.226361528038979
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
7593GO:0003700IEAFunctiontranscription factor activity
7593GO:0003700NASFunctiontranscription factor activity
7593GO:0005515IPIFunctionprotein binding
7593GO:0005634IEAComponentnucleus
7593GO:0006350IEAProcesstranscription
7593GO:0006355IEAProcessregulation of transcription, DNA-dependent
7593GO:0006355TASProcessregulation of transcription, DNA-dependent
7593GO:0008270IEAFunctionzinc ion binding
7593GO:0046872IEAFunctionmetal ion binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-51282NP_361012.1SCAN domain containing protein 1HPRD15298
NP_003413.223641NP_036449.1leucine zipper, down-regulated in cancer 1BIND209404
NP_932172.1--RAZ1HPRD01930
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
7593ZNF42_HUMANP28698IPR000694PRO_richProline-rich region
7593ZNF42_HUMANP28698IPR003309Treg_SCANTranscriptional regulator SCAN
7593ZNF42_HUMANP28698IPR007087Znf_C2H2Zinc finger, C2H2-type
7593ZNF42_HUMANP28698IPR007086Znf_C2H2_subZinc finger, C2H2-subtype

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