Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:7707
Official Symbol:ZNF148
Other Aliases:BERF-1|BFCOL1|HT-BETA|ZBP-89|ZFP148|pHZ-52
See related:HGNC:12933|MIM:601897|HPRD:03540
Chromosome:3
Location:3q21
Gene Description:zinc finger protein 148 (pHZ-52)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0522
ORGANISM:human
Entrez Gene ID:7707
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:58820
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
22661CBCerebellum32.982326507568436.0223922729492
22661CTXCerebral cortex100.085.1990814208984
22661HIPHippocampal region83.2070541381836100.0
22661HPFHippocampal formation89.7050094604492100.0
22661HYHypothalamus24.421388626098619.017463684082
22661LSXLateral septal complex32.422042846679724.4647312164307
22661MBMidbrain14.963104248046913.1198854446411
22661MYMedulla34.561481475830134.8426094055176
22661OLFOlfactory bulb100.0100.0
22661PPons26.66857147216826.0150585174561
22661PALPallidum27.129081726074223.9879417419434
22661RHPRetrohippocampal region100.092.5580902099609
22661sAMYStriatum-like amygdalar nuclei87.81176757812571.2295989990234
22661STRStriatum61.65801620483448.8563194274902
22661STRdStriatum dorsal region57.220363616943443.8463973999023
22661STRvStriatum ventral region86.464630126953170.7292709350586
22661THThalamus41.310184478759835.0588111877441
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
7707GO:0000122TASProcessnegative regulation of transcription from RNA polymerase II promoter
7707GO:0003676IEAFunctionnucleic acid binding
7707GO:0003677IEAFunctionDNA binding
7707GO:0003704TASFunctionspecific RNA polymerase II transcription factor activity
7707GO:0005634IEAComponentnucleus
7707GO:0005634TASComponentnucleus
7707GO:0005665TASComponentDNA-directed RNA polymerase II, core complex
7707GO:0006350IEAProcesstranscription
7707GO:0006355IEAProcessregulation of transcription, DNA-dependent
7707GO:0006355TASProcessregulation of transcription, DNA-dependent
7707GO:0006968TASProcesscellular defense response
7707GO:0008270IEAFunctionzinc ion binding
7707GO:0016563TASFunctiontranscriptional activator activity
7707GO:0046872IEAFunctionmetal ion binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-284119NP_036364.1polymerase I and transcript release factorHPRD04433
NP_068799.1284119-RNA polymerase I and transcript release factorHPRD03540
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
7707ZN148_HUMANQ9UQR1IPR001472NLS_BPBipartite nuclear localization signal
7707ZN148_HUMANQ9UQR1IPR007087Znf_C2H2Zinc finger, C2H2-type
7707ZN148_HUMANQ9UQR1IPR007086Znf_C2H2_subZinc finger, C2H2-subtype

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