Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:7857
Official Symbol:SCG2
Other Aliases:CHGC|SN|SgII
See related:HGNC:10575|MIM:118930|HPRD:06762
Chromosome:2
Location:2q35-q36
Gene Description:secretogranin II (chromogranin C)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0609
ORGANISM:human
Entrez Gene ID:7857
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:24765
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 2
KARG ID:EVIM0401
ORGANISM:human
Entrez Gene ID:7857
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12065639
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Upregulated
Fold Change:1.4 :: 1.1 :: 1.6 :: 1 :: 1 :: -1.5
KARG Evidence 3
KARG ID:EVIM0469
ORGANISM:human
Entrez Gene ID:7857
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12065639
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Motor Cortex
Drug Effects:Downregulated
Fold Change:-1.1 :: -1.1 :: -2.1 :: -6.4 :: -1.9
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
20254CBCerebellum29.066038131713944.0647735595703
20254CTXCerebral cortex46.579637527465846.8004302978516
20254HIPHippocampal region52.794353485107464.467830657959
20254HPFHippocampal formation44.347949981689550.1546897888184
20254HYHypothalamus100.0100.0
20254LSXLateral septal complex49.673902511596752.1320972442627
20254MBMidbrain82.18622207641699.7434577941895
20254MYMedulla73.489479064941497.790412902832
20254OLFOlfactory bulb100.0100.0
20254PPons67.340919494628987.7346611022949
20254PALPallidum69.312339782714892.123291015625
20254RHPRetrohippocampal region31.404148101806631.6715440750122
20254sAMYStriatum-like amygdalar nuclei100.0100.0
20254STRStriatum59.141721725463966.0258007049561
20254STRdStriatum dorsal region36.291755676269539.6223335266113
20254STRvStriatum ventral region89.546730041503986.760669708252
20254THThalamus46.267160415649445.7851028442383
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
7857GO:0005509IEAFunctioncalcium ion binding
7857GO:0009306TASProcessprotein secretion
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
7857SCG2_HUMANP13521IPR001990GraninChromogranin/secretogranin

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