Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:7913
Official Symbol:DEK
Other Aliases:D6S231E
See related:HGNC:2768|MIM:125264|HPRD:00503
Chromosome:6
Location:6p23
Gene Description:DEK oncogene (DNA binding)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0325
ORGANISM:human
Entrez Gene ID:7913
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:110052
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
110052CBCerebellum2.35430169105532.61510992050171
110052CTXCerebral cortex2.250584840774541.75032734870911
110052HIPHippocampal region2.275467872619632.18333029747009
110052HPFHippocampal formation1.675674200057981.4261519908905
110052HYHypothalamus0.2390047609806060.20748445391655
110052LSXLateral septal complex2.285187959671021.60757315158844
110052MBMidbrain0.8685640096664430.866782963275909
110052MYMedulla0.60231888294220.814377069473267
110052OLFOlfactory bulb3.014176368713382.62844896316528
110052PPons0.9894633293151861.11519968509674
110052PALPallidum1.386871695518491.63849580287933
110052RHPRetrohippocampal region0.7888844609260560.486189782619476
110052sAMYStriatum-like amygdalar nuclei0.9214176535606380.753290414810181
110052STRStriatum3.752914428710943.9190948009491
110052STRdStriatum dorsal region4.07399177551275.07266521453857
110052STRvStriatum ventral region4.172574043273932.64175367355347
110052THThalamus1.731119394302371.58167064189911
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
7913GO:0003677IEAFunctionDNA binding
7913GO:0003704TASFunctionspecific RNA polymerase II transcription factor activity
7913GO:0003723IEAFunctionRNA binding
7913GO:0005525IEAFunctionGTP binding
7913GO:0005634TASComponentnucleus
7913GO:0005786IEAComponentsignal recognition particle (sensu Eukaryota)
7913GO:0006357TASProcessregulation of transcription from RNA polymerase II promoter
7913GO:0006614IEAProcessSRP-dependent cotranslational protein targeting to membrane
7913GO:0007165TASProcesssignal transduction
7913GO:0019079TASProcessviral genome replication
7913GO:0042393IDAFunctionhistone binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-284307NP_001010879.1zinc finger protein interacting with K protein 1HPRD18321
NP_003463.1--HLA-A2HPRD00503
NP_003463.110250NP_005830.2serine/arginine repetitive matrix 1HPRD10441
NP_003463.110250NP_005830.2serine/arginine repetitive matrix 1HPRD00503
NP_003463.123524NP_057417.2splicing coactivator subunit SRm300HPRD06913
NP_003463.123524NP_057417.2splicing coactivator subunit SRm300HPRD00503
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
7913DEK_HUMANP35659IPR002038OsteopontinOsteopontin
7913DEK_HUMANP35659IPR003034SAP_DNA_bdDNA-binding SAP
7913DEK_HUMANP35659IPR003993treacleTreacher Collins syndrome protein Treacle

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