Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:80176
Official Symbol:SPSB1
Other Aliases:SSB-1|SSB1
See related:HGNC:30628|HPRD:18106
Chromosome:1
Location:1p36.22
Gene Description:splA/ryanodine receptor domain and SOCS box containing 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0280
ORGANISM:human
Entrez Gene ID:80176
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:74646
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
74646CBCerebellum23.517091751098632.3092231750488
74646CTXCerebral cortex11.1042480468758.25589084625244
74646HIPHippocampal region12.144583702087417.9332237243652
74646HPFHippocampal formation9.142880439758312.0827026367188
74646HYHypothalamus2.216184616088871.68210566043854
74646LSXLateral septal complex1.704788446426391.51543092727661
74646MBMidbrain5.574549198150635.61292695999146
74646MYMedulla12.37163925170914.7730541229248
74646OLFOlfactory bulb9.169467926025399.25109958648682
74646PPons10.668048858642612.2509498596191
74646PALPallidum2.012629985809331.83813631534576
74646RHPRetrohippocampal region4.384078025817874.58658266067505
74646sAMYStriatum-like amygdalar nuclei2.902275562286382.08279657363892
74646STRStriatum4.165801525115973.4547266960144
74646STRdStriatum dorsal region5.321992397308354.55282926559448
74646STRvStriatum ventral region2.433788537979131.72053682804108
74646THThalamus3.112221002578743.16928267478943
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
80176GO:0007242IEAProcessintracellular signaling cascade
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
80176IPR001870B302B302, (SPRY)-like
80176IPR001496SOCS_CSOCS protein, C-terminal
80176IPR003877SPRY_rcptSPla/RYanodine receptor SPRY
80176IPR001680WD40WD-40 repeat

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