Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:805
Official Symbol:CALM2
Other Aliases:CAMII|PHKD|PHKD2
See related:HGNC:1445|MIM:114182|HPRD:00242
Chromosome:2
Location:2p21
Gene Description:calmodulin 2 (phosphorylase kinase, delta)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0394
ORGANISM:human
Entrez Gene ID:805
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12065639
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Upregulated
Fold Change:1.5 :: 1.5 :: 1.5 :: 1.4 :: 1.1 :: 1.1
KARG Evidence 2
KARG ID:EVIM0462
ORGANISM:human
Entrez Gene ID:805
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12065639
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Motor Cortex
Drug Effects:Downregulated
Fold Change:-1.1 :: -1.1 :: -1.3 :: 2 :: 1.1
KARG Evidence 3
KARG ID:HOT0118
ORGANISM:human
Entrez Gene ID:805
Evidence Type:Whole Genome Association
Evidence ID Type:PUBMED
Evidence ID:NA
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 4
KARG ID:HOT0108
ORGANISM:human
Entrez Gene ID:805
Evidence Type:Whole Genome Association
Evidence ID Type:PUBMED
Evidence ID:NA
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-5475NP_006231.2serine/threonine protein phosphatase with EF-hand motifs 1 isoform 1HPRD02118
NP_001734.1--EDF1HPRD00242
NP_001734.1--KCNQ3HPRD00242
NP_001734.1--KCNQ5HPRD00242
NP_001734.127130--BIND217612
NP_001734.19657AAW47233.1nephrocystin 5BIND217480
NP_001734.12915BAA05892.1Metabotropic Glutamate Receptor Subtype 5b (mGluR5b)HPRD00242
NP_001734.12915BAA05892.1Metabotropic Glutamate Receptor Subtype 5b (mGluR5b)HPRD04980
NP_001734.12099NP_000116.1estrogen receptor 1HPRD00589
NP_001734.12099NP_000116.1estrogen receptor 1HPRD00242
NP_001734.12100NP_001428.1estrogen receptor beta isoform 1HPRD00242
NP_001734.12100NP_001428.1estrogen receptor beta isoform 1HPRD03390
NP_001734.14082NP_002347.4myristoylated alanine-rich protein kinase C substrateHPRD00242
NP_001734.14082NP_002347.4myristoylated alanine-rich protein kinase C substrateHPRD07519
NP_001734.14618NP_002460.1myogenic factor 6 (herculin)HPRD00242
NP_001734.14618NP_002460.1myogenic factor 6 (herculin)HPRD01169
NP_001734.14654NP_002469.2myogenic differentiation 1HPRD00242
NP_001734.14654NP_002469.2myogenic differentiation 1HPRD01166
NP_001734.14656NP_002470.2myogeninHPRD00242
NP_001734.14656NP_002470.2myogeninHPRD01167
NP_001734.14760NP_002491.1neurogenic differentiation 1HPRD00242
NP_001734.14760NP_002491.1neurogenic differentiation 1HPRD03428
NP_001734.15865NP_002858.2RAB3B, member RAS oncogene familyHPRD00242
NP_001734.15865NP_002858.2RAB3B, member RAS oncogene familyHPRD01540
NP_001734.16925NP_003190.1transcription factor 4 isoform bHPRD00242
NP_001734.16925NP_003190.1transcription factor 4 isoform bHPRD03780
NP_001734.13785NP_004509.2potassium voltage-gated channel KQT-like protein 2 isoform cHPRD03757
NP_001734.13785NP_004509.2potassium voltage-gated channel KQT-like protein 2 isoform cHPRD00242
NP_001734.14617NP_005584.1myogenic factor 5HPRD00242
NP_001734.14617NP_005584.1myogenic factor 5HPRD01168
NP_001734.15116NP_006022.2pericentrin BHPRD05804
NP_001734.15116NP_006022.2pericentrin BHPRD00242
NP_001734.15470NP_006230.2serine/threonine protein phosphatase with EF-hand motifs 2 isoform aHPRD03771
NP_001734.15470NP_006230.2serine/threonine protein phosphatase with EF-hand motifs 2 isoform aHPRD00242
NP_001734.15475NP_006231.2serine/threonine protein phosphatase with EF-hand motifs 1 isoform 1HPRD00242
NP_001734.156479NP_062816.2potassium voltage-gated channel, KQT-like subfamily, member 5HPRD16241
NP_001734.12917NP_870989.1glutamate receptor, metabotropic 7 isoform b precursorHPRD00242
NP_001734.12917NP_870989.1glutamate receptor, metabotropic 7 isoform b precursorHPRD04979
NP_001734.1155030NP_579876.2matrix--
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
805CALM_HUMANP62158IPR003299Calflagin_bdFlagellar calcium-binding protein (calflagin)
805CALM_HUMANP62158IPR013567EF_hand_assoc_2EF hand associated, type-2
805CALM_HUMANP62158IPR002048EF_hand_Ca_bdCalcium-binding EF-hand
805CALM_HUMANP62158IPR013684Miro-likeMiro-like
805CALM_HUMANP62158IPR013623NADPH_OxNADPH oxidase Respiratory burst
805CALM_HUMANP62158IPR001125RecoverinRecoverin

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