Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:821
Official Symbol:CANX
Other Aliases:CNX|FLJ26570|IP90|P90
See related:HGNC:1473|MIM:114217|HPRD:00252
Chromosome:5
Location:5q35
Gene Description:calnexin
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0407
ORGANISM:human
Entrez Gene ID:821
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:29144
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
12330CBCerebellum100.0100.0
12330CTXCerebral cortex100.0100.0
12330HIPHippocampal region100.0100.0
12330HPFHippocampal formation100.0100.0
12330HYHypothalamus100.0100.0
12330LSXLateral septal complex100.0100.0
12330MBMidbrain100.0100.0
12330MYMedulla100.0100.0
12330OLFOlfactory bulb100.0100.0
12330PPons100.0100.0
12330PALPallidum100.0100.0
12330RHPRetrohippocampal region100.0100.0
12330sAMYStriatum-like amygdalar nuclei100.0100.0
12330STRStriatum100.0100.0
12330STRdStriatum dorsal region100.0100.0
12330STRvStriatum ventral region100.0100.0
12330THThalamus100.0100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
821GO:0005509IEAFunctioncalcium ion binding
821GO:0005509TASFunctioncalcium ion binding
821GO:0005529IEAFunctionsugar binding
821GO:0005783IDAComponentendoplasmic reticulum
821GO:0005783IEAComponentendoplasmic reticulum
821GO:0006457IEAProcessprotein folding
821GO:0009306TASProcessprotein secretion
821GO:0016020IEAComponentmembrane
821GO:0016021IEAComponentintegral to membrane
821GO:0051082IEAFunctionunfolded protein binding
821GO:0051082NASFunctionunfolded protein binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-2157NP_000123.1coagulation factor VIII isoform a precursorHPRD02384
-3655NP_000201.1integrin alpha chain, alpha 6HPRD00945
-7253NP_000360.1thyroid stimulating hormone receptorHPRD04537
-1244NP_000383.1ATP-binding cassette, sub-family C (CFTR/MRP), member 2HPRD03065
-915NP_000723.1CD3D antigen, delta polypeptide (TiT3 complex)HPRD01730
-2890NP_000818.1glutamate receptor, ionotropic, AMPA 1HPRD00695
-3359NP_000860.15-hydroxytryptamine (serotonin) receptor 3A isoform b precursorHPRD08917
-912NP_001757.1CD1D antigen, d polypeptideHPRD01780
-3938NP_002290.2lactase-phlorizin hydrolase preproproteinHPRD04437
-4035NP_002323.1low density lipoprotein-related protein 1HPRD00138
-7038NP_003226.3thyroglobulinHPRD01782
-2923NP_005304.3protein disulfide isomerase-associated 3 precursorHPRD03625
-6513NP_006507.1solute carrier family 2 (facilitated glucose transporter), member 1HPRD00683
-2902NP_015566.1NMDA receptor 1 isoform NR1-3 precursorHPRD15926
-27230NP_055260.1stress-associated endoplasmic reticulum protein 1HPRD18037
-3688NP_391987.1integrin beta 1 isoform 1C-1 precursorHPRD00628
NP_001737.1--IFN gamma receptorHPRD00252
NP_001737.1--MHC Class IHPRD00252
NP_001737.1--PLPHPRD00252
NP_001737.1--Apo-B29HPRD00252
NP_001737.1-AAL29687.1Measles virus G954 haemagglutinin (H) mRNA, complete cds.BIND19085
NP_001737.13655-Integrin alpha 6HPRD00252
NP_001737.13688-Integrin beta 1HPRD00252
NP_001737.1915-CD3 DeltaHPRD00252
NP_001737.16513-Solute carrier family,member 1HPRD00252
NP_001737.12157-Coagulation factor VIIIHPRD00252
NP_001737.12890-Glutamate receptor, ionotropic AMPA 1HPRD00252
NP_001737.17038-ThyroglobulinHPRD00252
NP_001737.13938-LactaseHPRD00252
NP_001737.11244-ATP binding cassette, sub family C, member 2HPRD00252
NP_001737.1912-CD1dHPRD00252
NP_001737.13359-Serotonin 5-HT-3 receptorHPRD00252
NP_001737.17253-Thyroid stimulating hormone receptorHPRD00252
NP_001737.14035-Low density lipoprotein receptor-related protein 1HPRD00252
NP_001737.16955AAH71758.1TRA@ proteinHPRD00252
NP_001737.16955AAH71758.1TRA@ proteinHPRD01736
NP_001737.16521NP_000333.1solute carrier family 4, anion exchanger, member 1HPRD00252
NP_001737.16521NP_000333.1solute carrier family 4, anion exchanger, member 1HPRD00175
NP_001737.17253NP_000360.1thyroid stimulating hormone receptorBIND19152
NP_001737.11080NP_000483.2cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7)BIND19109
NP_001737.11080NP_000483.2cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7)BIND130574
NP_001737.17018NP_001054.1transferrinHPRD00252
NP_001737.17018NP_001054.1transferrinHPRD01811
NP_001737.13732NP_002222.1CD82 antigen isoform 1HPRD09004
NP_001737.13732NP_002222.1CD82 antigen isoform 1HPRD00252
NP_001737.15589NP_002734.2protein kinase C substrate 80K-H isoform 1HPRD03518
NP_001737.15589NP_002734.2protein kinase C substrate 80K-H isoform 1HPRD00252
NP_001737.18720NP_003782.1membrane-bound transcription factor site-1 protease isoform 1 preproproteinHPRD04522
NP_001737.18720NP_003782.1membrane-bound transcription factor site-1 protease isoform 1 preproproteinHPRD00252
NP_001737.12923NP_005304.3protein disulfide isomerase-associated 3 precursorHPRD00252
NP_001737.12923NP_005304.3protein disulfide isomerase-associated 3 precursorBIND172370
NP_001737.14018NP_005568.1lipoprotein, Lp(a)HPRD00252
NP_001737.14018NP_005568.1lipoprotein, Lp(a)HPRD01063
NP_001737.110134NP_005736.3B-cell receptor-associated protein 31HPRD00252
NP_001737.110134NP_005736.3B-cell receptor-associated protein 31HPRD02319
NP_001737.110148NP_005746.2Epstein-Barr virus induced gene 3 precursorHPRD12051
NP_001737.19695Q92611ER degradation-enhancing alpha-mannosidase-like 1.HPRD00252
NP_001737.19695Q92611ER degradation-enhancing alpha-mannosidase-like 1.HPRD09644
NP_001737.11489800NP_056922.1fusion proteinBIND19086
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
821CALX_HUMANP27824IPR001580Calret/calnexCalreticulin/calnexin

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