Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:826
Official Symbol:CAPNS1
Other Aliases:30K|CALPAIN4|CANP|CANPS|CAPN4|CDPS
See related:HGNC:1481|MIM:114170|HPRD:00240
Chromosome:19
Location:19q13.12
Gene Description:calpain, small subunit 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0239
ORGANISM:human
Entrez Gene ID:826
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:12336
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 2
KARG ID:EVIM0940
ORGANISM:human
Entrez Gene ID:826
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Upregulated
Fold Change:1.4 :: 1.5
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
12336CBCerebellum50.050.0
12336CTXCerebral cortex50.050.0
12336HIPHippocampal region50.050.0
12336HPFHippocampal formation50.050.0
12336HYHypothalamus50.050.0
12336LSXLateral septal complex50.050.0
12336MBMidbrain50.050.0
12336MYMedulla50.050.0
12336OLFOlfactory bulb50.050.0
12336PPons50.050.0
12336PALPallidum50.050.0
12336RHPRetrohippocampal region50.050.0
12336sAMYStriatum-like amygdalar nuclei50.050.0
12336STRStriatum50.050.0
12336STRdStriatum dorsal region50.046.350170135498
12336STRvStriatum ventral region50.048.5586433410645
12336THThalamus50.050.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
826GO:0004198TASFunctioncalpain activity
826GO:0005509IEAFunctioncalcium ion binding
826GO:0008284TASProcesspositive regulation of cell proliferation
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-3561NP_000197.1interleukin 2 receptor, gamma precursorHPRD02391
NP_001740.13561-Interleukin 2 receptor, gammaHPRD00240
NP_001740.1831NP_001741.3calpastatin isoform aHPRD00233
NP_001740.1831NP_001741.3calpastatin isoform aHPRD00240
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
826CPNS1_HUMANP04632IPR013567EF_hand_assoc_2EF hand associated, type-2
826CPNS1_HUMANP04632IPR002048EF_hand_Ca_bdCalcium-binding EF-hand
826CPNS1_HUMANP04632IPR002952EggshellEggshell protein
826CPNS1_HUMANP04632IPR013684Miro-likeMiro-like
826CPNS1_HUMANP04632IPR013623NADPH_OxNADPH oxidase Respiratory burst

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