Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:8326
Official Symbol:FZD9
Other Aliases:FZD3
See related:HGNC:4047|MIM:601766|HPRD:03460
Chromosome:7
Location:7q11.23
Gene Description:frizzled homolog 9 (Drosophila)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0415
ORGANISM:human
Entrez Gene ID:8326
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12065639
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Downregulated
Fold Change:-1.3 :: -1.4 :: -1.2 :: -1.4 :: -1.4 :: -1.4
KARG Evidence 2
KARG ID:EVIM0483
ORGANISM:human
Entrez Gene ID:8326
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12065639
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Motor Cortex
Drug Effects:Downregulated
Fold Change:1.1 :: 1 :: -1.2 :: -1.8 :: -1.4
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
8326GO:0004872IEAFunctionreceptor activity
8326GO:0004926IEAFunctionnon-G-protein coupled 7TM receptor activity
8326GO:0004930IEAFunctionG-protein coupled receptor activity
8326GO:0005886TASComponentplasma membrane
8326GO:0007186IEAProcessG-protein coupled receptor protein signaling pathway
8326GO:0007222TASProcessfrizzled signaling pathway
8326GO:0007275IEAProcessdevelopment
8326GO:0007399TASProcessnervous system development
8326GO:0016021TASComponentintegral to membrane
8326GO:0042813TASFunctionWnt receptor activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
8326FZD9_HUMANO00144IPR000735Adren_rcpt_A2CAdrenergic receptor, alpha-2C
8326FZD9_HUMANO00144IPR000539FrizzledFrizzled protein
8326FZD9_HUMANO00144IPR000024Fz_domainFrizzled CRD region
8326FZD9_HUMANO00144IPR000832GPCR_secretinGPCR, family 2, secretin-like

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