Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:84152
Official Symbol:PPP1R1B
Other Aliases:DARPP-32|DARPP32|FLJ20940
See related:HGNC:9287|MIM:604399|HPRD:05097
Chromosome:17
Location:17q12
Gene Description:protein phosphatase 1, regulatory (inhibitor) subunit 1B (dopamine and cAMP regulated phosphoprotein, DARPP-32)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0072
ORGANISM:human
Entrez Gene ID:84152
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:19049
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
19049CBCerebellum68.5601863861084100.0
19049CTXCerebral cortex100.0100.0
19049HIPHippocampal region70.214326858520586.3205490112305
19049HPFHippocampal formation80.898584365844793.9105224609375
19049HYHypothalamus53.021152257919353.1021349430084
19049LSXLateral septal complex79.067277908325289.9036865234375
19049MBMidbrain62.077131271362362.2283039093018
19049MYMedulla68.718347549438574.2967739105225
19049OLFOlfactory bulb100.0100.0
19049PPons52.090055942535456.6232972145081
19049PALPallidum72.992837905883893.296085357666
19049RHPRetrohippocampal region92.8115158081055100.0
19049sAMYStriatum-like amygdalar nuclei77.808271408081190.122730255127
19049STRStriatum100.0100.0
19049STRdStriatum dorsal region100.0100.0
19049STRvStriatum ventral region100.0100.0
19049THThalamus59.094134330749559.0700426101685
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
84152GO:0004860TASFunctionprotein kinase inhibitor activity
84152GO:0004864TASFunctionprotein phosphatase inhibitor activity
84152GO:0005737NASComponentcytoplasm
84152GO:0007165TASProcesssignal transduction
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_115568.2--PP-1CHPRD05097
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
84152
84152IPPD_HUMANQ9UD71IPR008466DARPP-32Protein phosphatase inhibitor, 1DARPP-32

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