Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:8437
Official Symbol:RASAL1
Other Aliases:RASAL
See related:HGNC:9873|MIM:604118|HPRD:04986
Chromosome:12
Location:12q23-q24
Gene Description:RAS protein activator like 1 (GAP1 like)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0270
ORGANISM:human
Entrez Gene ID:8437
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:19415
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
19415CBCerebellum6.583698511123666.03543877601624
19415CTXCerebral cortex100.093.839599609375
19415HIPHippocampal region51.623224258422969.9463043212891
19415HPFHippocampal formation89.72687911987391.9863891601562
19415HYHypothalamus30.175814628601114.7468566894531
19415LSXLateral septal complex41.551216125488316.4142332077026
19415MBMidbrain9.355658531188964.63225722312927
19415MYMedulla6.641220450401313.83348208665848
19415OLFOlfactory bulb85.809913635253964.5350093841553
19415PPons6.402632713317873.75062787532806
19415PALPallidum33.260021209716816.9014272689819
19415RHPRetrohippocampal region100.0100.0
19415sAMYStriatum-like amygdalar nuclei100.072.3130493164062
19415STRStriatum42.026748657226622.8383502960205
19415STRdStriatum dorsal region17.408255100250210.2837846279144
19415STRvStriatum ventral region69.620079040527331.0397758483887
19415THThalamus18.791686534881610.7563033103943
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
8437GO:0005099TASFunctionRas GTPase activator activity
8437GO:0005543TASFunctionphospholipid binding
8437GO:0007242IEAProcessintracellular signaling cascade
8437GO:0008270IEAFunctionzinc ion binding
8437GO:0046872IEAFunctionmetal ion binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
8437RASL1_HUMANO95294IPR001562BTKTec/Btk
8437RASL1_HUMANO95294IPR000008C2C2
8437RASL1_HUMANO95294IPR001849PHPleckstrin-like
8437RASL1_HUMANO95294IPR013583PRT_C_plnPhosphoribosyltransferase C-terminal, plant
8437RASL1_HUMANO95294IPR001936RasGAPRas GTPase-activating protein
8437RASL1_HUMANO95294IPR001565SynaptotagminSynaptotagmin

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