Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:8450
Official Symbol:CUL4B
Other Aliases:KIAA0695
See related:HGNC:2555|MIM:300304|HPRD:02251
Chromosome:X
Location:Xq23
Gene Description:cullin 4B
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0091
ORGANISM:human
Entrez Gene ID:8450
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15009677
Addiction Drug:COCAINE
Addiction Drug Detail:COCAINE ABUSE
Addiction Brain Area:Nucleus Accumbens
Drug Effects:Upregulated
Fold Change:0.25 :: -0.04 :: 0.03 :: 0.34 :: 0.45 :: 0.47 :: 0.60 :: 0.09 :: -0.01 :: 0.28
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
72584CBCerebellum55.0332527160645100.0
72584CTXCerebral cortex56.556411743164155.7715530395508
72584HIPHippocampal region44.62261581420972.988883972168
72584HPFHippocampal formation38.55852127075257.0755958557129
72584HYHypothalamus59.520412445068480.2196350097656
72584LSXLateral septal complex49.359764099121150.9950103759766
72584MBMidbrain20.171512603759824.6350955963135
72584MYMedulla23.055376052856430.1485958099365
72584OLFOlfactory bulb72.994171142578186.3276596069336
72584PPons19.670589447021525.8318214416504
72584PALPallidum25.915588378906228.2170009613037
72584RHPRetrohippocampal region27.698932647705133.328914642334
72584sAMYStriatum-like amygdalar nuclei68.006584167480576.6825180053711
72584STRStriatum26.717590332031226.7654361724854
72584STRdStriatum dorsal region12.572841644287111.7826824188232
72584STRvStriatum ventral region41.059257507324237.4477615356445
72584THThalamus23.958921432495129.2640399932861
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
8450GO:0005515IPIFunctionprotein binding
8450GO:0005554NDFunctionmolecular function unknown
8450GO:0006512IEAProcessubiquitin cycle
8450GO:0007049NASProcesscell cycle
8450GO:0008372NDComponentcellular component unknown
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_003579.255832NP_060918.2TIP120 proteinHPRD06983
NP_003579.255832NP_060918.2TIP120 proteinHPRD02251
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
8450IPR001373CullinCullin

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