Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:8502
Official Symbol:PKP4
Other Aliases:FLJ31261|FLJ42243|p0071
See related:HGNC:9026|MIM:604276|HPRD:05043
Chromosome:2
Location:2q23-q31
Gene Description:plakophilin 4
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0033
ORGANISM:human
Entrez Gene ID:8502
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:227937
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
227937CBCerebellum1.2428001165391.78876841068268
227937CTXCerebral cortex1.456987619400021.22713708877563
227937HIPHippocampal region0.8209973573684690.977083265781403
227937HPFHippocampal formation0.6498738527297970.722214877605438
227937HYHypothalamus0.3752292096614840.428043812513351
227937LSXLateral septal complex0.723423242568970.511104345321655
227937MBMidbrain0.5252006649971010.60186094045639
227937MYMedulla0.9415320158004760.876650810241699
227937OLFOlfactory bulb5.263423442840584.81670427322388
227937PPons0.6813565492630.978745818138123
227937PALPallidum0.3761196732521060.30138623714447
227937RHPRetrohippocampal region0.3638592958450320.342956483364105
227937sAMYStriatum-like amygdalar nuclei0.5538906455039980.459463685750961
227937STRStriatum0.6237091422080990.457917332649231
227937STRdStriatum dorsal region0.2642441093921660.212105602025986
227937STRvStriatum ventral region1.732316732406621.12513554096222
227937THThalamus0.6515311598777770.515632271766663
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
8502GO:0005198IEAFunctionstructural molecule activity
8502GO:0005488IEAFunctionbinding
8502GO:0005515IEAFunctionprotein binding
8502GO:0005856IEAComponentcytoskeleton
8502GO:0005911TASComponentintercellular junction
8502GO:0007155NASProcesscell adhesion
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-23037NP_835260.1PDZ domain containing 3 isoform aHPRD10142
NP_003619.1--PAPINHPRD05043
NP_003619.123037-PDZ domain containing 3HPRD05043
NP_003619.155914AAK69431.1densin-180-like proteinHPRD05043
NP_003619.155914AAK69431.1densin-180-like proteinHPRD06090
NP_003619.123037NP_835260.1PDZ domain containing 3 isoform aBIND130942
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
8502PKP4_HUMANQ99569IPR000225ArmadilloArmadillo

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