Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:8556
Official Symbol:CDC14A
Other Aliases:Cdc14A1|Cdc14A2|cdc14|hCDC14
See related:HGNC:1718|MIM:603504|HPRD:04614
Chromosome:1
Location:1p21
Gene Description:CDC14 cell division cycle 14 homolog A (S. cerevisiae)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0299
ORGANISM:human
Entrez Gene ID:8556
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15816859
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Prefrontal Cortex
Drug Effects:Downregulated
Fold Change:-0.56
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
8556GO:0000074TASProcessregulation of progression through cell cycle
8556GO:0004725IEAFunctionprotein tyrosine phosphatase activity
8556GO:0005634TASComponentnucleus
8556GO:0006470IEAProcessprotein amino acid dephosphorylation
8556GO:0007049IEAProcesscell cycle
8556GO:0008138IEAFunctionprotein tyrosine/serine/threonine phosphatase activity
8556GO:0008283TASProcesscell proliferation
8556GO:0016787IEAFunctionhydrolase activity
8556GO:0051301IEAProcesscell division
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_201569.151343NP_057347.2Fzr1 proteinHPRD04614
NP_201569.151343NP_057347.2Fzr1 proteinHPRD04687
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
8556IPR000340DS_phosphataseDual specificity protein phosphatase
8556IPR000387TYR_phosphataseTyrosine specific protein phosphatase and dual specificity protein phosphatase
8556CC14A_HUMANQ9UNH5IPR000340DS_phosphataseDual specificity protein phosphatase
8556CC14A_HUMANQ9UNH5IPR000387TYR_phosphataseTyrosine specific protein phosphatase and dual specificity protein phosphatase

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