Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:8564
Official Symbol:KMO
Other Aliases:dJ317G22.1
See related:HGNC:6381|MIM:603538|HPRD:04642
Chromosome:1
Location:1q42-q44
Gene Description:kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0596
ORGANISM:human
Entrez Gene ID:8564
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:59113
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
98256CBCerebellum19.199222564697323.0593090057373
98256CTXCerebral cortex22.13127517700215.4684047698975
98256HIPHippocampal region13.220643043518113.1623811721802
98256HPFHippocampal formation15.550264358520514.1089315414429
98256HYHypothalamus10.62077903747567.36887168884277
98256LSXLateral septal complex5.889401435852055.44476175308228
98256MBMidbrain5.644433498382576.35999298095703
98256MYMedulla10.083244323730511.0848751068115
98256OLFOlfactory bulb42.12787246704134.5346221923828
98256PPons10.351920127868710.757830619812
98256PALPallidum12.36474800109869.57703113555908
98256RHPRetrohippocampal region20.435808181762716.0548763275146
98256sAMYStriatum-like amygdalar nuclei11.75639152526868.28640651702881
98256STRStriatum10.69071674346927.39858293533325
98256STRdStriatum dorsal region10.74641895294197.45033884048462
98256STRvStriatum ventral region14.53902053833018.79343509674072
98256THThalamus11.83272933959969.16870784759521
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
8564GO:0004497IEAFunctionmonooxygenase activity
8564GO:0004502TASFunctionkynurenine 3-monooxygenase activity
8564GO:0006118IEAProcesselectron transport
8564GO:0008152IEAProcessmetabolism
8564GO:0008152TASProcessmetabolism
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
8564IPR000759Adrndx_reductaseAdrenodoxin reductase
8564IPR006076Fad_oxredFAD dependent oxidoreductase
8564IPR002938mOase_FAD_bdMonooxygenase, FAD-binding
8564IPR003042Rng_hydrolaseAromatic-ring hydroxylase

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