Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:8566
Official Symbol:PDXK
Other Aliases:C21orf97|PKH|PNK
See related:HGNC:8819|MIM:179020|HPRD:01526
Chromosome:21
Location:21q22.3
Gene Description:pyridoxal (pyridoxine, vitamin B6) kinase
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0025
ORGANISM:human
Entrez Gene ID:8566
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:216134
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
216134CBCerebellum41.887219111124743.0703144073486
216134CTXCerebral cortex43.942830085754441.7547456423442
216134HIPHippocampal region49.322129567464244.8482475280762
216134HPFHippocampal formation49.98051802317345.74631468455
216134HYHypothalamus66.833773295084658.6652851104736
216134LSXLateral septal complex63.465268770853759.3005361557007
216134MBMidbrain57.176453908284554.8244915008545
216134MYMedulla51.203580856323250.2800232569377
216134OLFOlfactory bulb56.304132461547947.2910982767741
216134PPons52.499231974283950.3660408655802
216134PALPallidum61.979220072428458.4137725830078
216134RHPRetrohippocampal region51.399070103963247.0940116246541
216134sAMYStriatum-like amygdalar nuclei54.530934651692748.0166018803914
216134STRStriatum50.721695264180545.2797880172729
216134STRdStriatum dorsal region43.575577735900940.1831822395325
216134STRvStriatum ventral region68.345642089843854.5615361531576
216134THThalamus43.418481508890841.3848695755005
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
8566GO:0000166IEAFunctionnucleotide binding
8566GO:0005524IEAFunctionATP binding
8566GO:0008270IEAFunctionzinc ion binding
8566GO:0008478TASFunctionpyridoxal kinase activity
8566GO:0016740IEAFunctiontransferase activity
8566GO:0046872IEAFunctionmetal ion binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
8566PDXK_HUMANO00764IPR000631carb_kinaseCarbohydrate kinase
8566PDXK_HUMANO00764IPR011611PfkB_regionPfkB

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