Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:8642
Official Symbol:DCHS1
Other Aliases:CDH25|FIB1|FLJ11790|KIAA1773|PCDH16
See related:HGNC:13681|MIM:603057|HPRD:04341
Chromosome:11
Location:11p15.4
Gene Description:dachsous 1 (Drosophila)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0916
ORGANISM:human
Entrez Gene ID:8642
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Upregulated
Fold Change:1.4 :: 1.8
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
233651CBCerebellum0.6432659626007081.13173460960388
233651CTXCerebral cortex0.8149206638336180.996310591697693
233651HIPHippocampal region1.303632020950321.41114830970764
233651HPFHippocampal formation0.8716127872467040.891117036342621
233651HYHypothalamus0.4464020729064940.659622967243195
233651LSXLateral septal complex1.483595013618472.30723261833191
233651MBMidbrain0.3015092015266420.445543140172958
233651MYMedulla0.3820652365684510.555478155612946
233651OLFOlfactory bulb1.250210642814641.14665830135345
233651PPons0.2540799081325530.345529466867447
233651PALPallidum0.3331398963928220.266149520874023
233651RHPRetrohippocampal region0.3211438059806820.330027788877487
233651sAMYStriatum-like amygdalar nuclei0.2001473754644390.214959681034088
233651STRStriatum0.6271563768386840.854936242103577
233651STRdStriatum dorsal region0.3841932415962220.600038349628448
233651STRvStriatum ventral region0.9554569721221920.970273733139038
233651THThalamus0.7686072587966921.32442677021027
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
8642GO:0005509IEAFunctioncalcium ion binding
8642GO:0005515IEAFunctionprotein binding
8642GO:0007155IEAProcesscell adhesion
8642GO:0007156IEAProcesshomophilic cell adhesion
8642GO:0016020NASComponentmembrane
8642GO:0016021IEAComponentintegral to membrane
8642GO:0016339NASProcesscalcium-dependent cell-cell adhesion
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
8642PCD16_HUMANQ96JQ0IPR002126CadherinCadherin
8642PCD16_HUMANQ96JQ0IPR013164Cadherin_2Cadherin-like
8642PCD16_HUMANQ96JQ0IPR013585ProtocadherinProtocadherin

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