Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:8655
Official Symbol:DYNLL1
Other Aliases:DLC1|DLC8|DNCL1|DNCLC1|LC8|LC8a|MGC126137|MGC126138|PIN|hdlc1
See related:HGNC:15476|MIM:601562|HPRD:03334
Chromosome:12
Location:12q24.23
Gene Description:dynein, light chain, LC8-type 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIP0215
ORGANISM:human
Entrez Gene ID:8655
Evidence Type:Proteomics
Evidence ID Type:PUBMED
Evidence ID:15542695
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Whole Brain
Drug Effects:Downregulated
Fold Change:0.43
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
8655GO:0003777IEAFunctionmicrotubule motor activity
8655GO:0005874IEAComponentmicrotubule
8655GO:0007017IEAProcessmicrotubule-based process
8655GO:0030286IEAComponentdynein complex
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-23139AAH65499.1MAST205 proteinHPRD11294
-9026NP_003950.1huntingtin interacting protein-1-relatedHPRD10412
-9112NP_004680.1metastasis associated proteinHPRD04633
-10383NP_006079.1tubulin, beta, 2HPRD04043
-26052NP_056384.2dynamin 3HPRD13241
-56288NP_062565.2partitioning-defective protein 3 homologHPRD05994
-10243NP_065857.1gephyrin isoform 1HPRD04893
-57619NP_065910.1shroomHPRD07053
NP_003737.1--DLGAP1HPRD03334
NP_003737.1--CACNB1HPRD03334
NP_003737.1--CYLN2HPRD03334
NP_003737.1--DNM3HPRD03334
NP_003737.1--GRIN3AHPRD03334
NP_003737.1--Glutamate dehydrogenaseHPRD03334
NP_003737.1--HIP12HPRD03334
NP_003737.1--HSPA8HPRD03334
NP_003737.1--MAST2HPRD03334
NP_003737.1--NMDAR-LHPRD03334
NP_003737.1--Tubulin betaHPRD03334
NP_003737.1-AAK55102.1phosphoproteinBIND50227
NP_003737.1-BAC53866.1phosphoproteinBIND50228
NP_003737.19229--BIND257601
NP_003737.110243-GephyrinHPRD03334
NP_003737.110383-Tubulin, beta-2HPRD03334
NP_003737.156288-PARD3HPRD03334
NP_003737.157619-ShroomHPRD03334
NP_003737.19112-Metastasis associated protein MTA1HPRD03334
NP_003737.18655NP_003737.1dynein light chain 1BIND154025
NP_003737.19229NP_004737.2discs large homolog-associated protein 1 isoform alphaBIND296522
NP_003737.19924NP_055686.2ubiquitin specific protease 52BIND257604
NP_003737.184817NP_116120.1thioredoxin-like 5HPRD11656
NP_003737.110018NP_619527.1BCL2-like 11 isoform 1HPRD03334
NP_003737.110018NP_619527.1BCL2-like 11 isoform 1HPRD04828
NP_003737.111142NP_861521.1cAMP-dependent protein kinase inhibitor gammaBIND300747
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
8655DYL1_HUMANP63167IPR001372Dynein_light1Dynein light chain, type 1

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