Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:8777
Official Symbol:MPDZ
Other Aliases:DKFZp781P216|FLJ25909|FLJ34626|FLJ90240|MUPP1
See related:HGNC:7208|MIM:603785|HPRD:09155
Chromosome:9
Location:9p24-p22
Gene Description:multiple PDZ domain protein
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0158
ORGANISM:human
Entrez Gene ID:8777
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:17475
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
17475CBCerebellum21.220529556274452.2593269348145
17475CTXCerebral cortex69.407791137695361.8358917236328
17475HIPHippocampal region65.9981002807617100.0
17475HPFHippocampal formation63.929878234863382.7528457641602
17475HYHypothalamus15.768071174621611.8112087249756
17475LSXLateral septal complex24.246604919433620.7672424316406
17475MBMidbrain17.394262313842816.3415603637695
17475MYMedulla29.198120117187535.0892791748047
17475OLFOlfactory bulb55.142932891845751.2657470703125
17475PPons23.619243621826226.7829265594482
17475PALPallidum20.557476043701219.7710514068604
17475RHPRetrohippocampal region59.841461181640654.5237312316895
17475sAMYStriatum-like amygdalar nuclei28.733995437622129.6974563598633
17475STRStriatum13.240251541137712.1618299484253
17475STRdStriatum dorsal region10.889747619628910.0109968185425
17475STRvStriatum ventral region7.334609031677255.48548555374146
17475THThalamus40.872966766357437.2345771789551
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
8777GO:0005515IPIFunctionprotein binding
8777GO:0005923IEAComponenttight junction
8777GO:0016020IEAComponentmembrane
8777GO:0019717IEAComponentsynaptosome
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-9076NP_066924.1claudin 1HPRD04760
NP_003820.1--JAM1HPRD09155
NP_003820.1--TAPP2HPRD09155
NP_003820.19076-Claudin 1HPRD09155
NP_003820.159338NP_067635.2pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1HPRD09155
NP_003820.159338NP_067635.2pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1HPRD09686
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
8777MPDZ_HUMANO75970IPR001478PDZPDZ/DHR/GLGF

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