Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:8787
Official Symbol:RGS9
Other Aliases:MGC111763|MGC26458|PERRS|RGS9L
See related:HGNC:10004|MIM:604067|HPRD:04962
Chromosome:17
Location:17q23-q24
Gene Description:regulator of G-protein signalling 9
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0281
ORGANISM:human
Entrez Gene ID:8787
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15816859
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Prefrontal Cortex
Drug Effects:Downregulated
Fold Change:-0.54
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
19739CBCerebellum2.870603799819953.31552702188492
19739CTXCerebral cortex8.884136676788337.46432685852051
19739HIPHippocampal region6.767194271087657.06734013557434
19739HPFHippocampal formation8.308799028396617.54237222671509
19739HYHypothalamus17.163776874542214.2805614471436
19739LSXLateral septal complex18.227962493896525.5382518768311
19739MBMidbrain6.19957470893865.28247249126434
19739MYMedulla5.936402440071118.01987624168396
19739OLFOlfactory bulb15.865427970886212.9024085998535
19739PPons6.686642885208137.95928621292114
19739PALPallidum24.367349624633828.8759603500366
19739RHPRetrohippocampal region10.32198905944827.80741405487061
19739sAMYStriatum-like amygdalar nuclei22.480248451232917.6908240318298
19739STRStriatum100.0100.0
19739STRdStriatum dorsal region100.0100.0
19739STRvStriatum ventral region100.0100.0
19739THThalamus2.45519101619722.15829885005951
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
8787GO:0004871IEAFunctionsignal transducer activity
8787GO:0005096TASFunctionGTPase activator activity
8787GO:0005834IEAComponentheterotrimeric G-protein complex
8787GO:0007242IEAProcessintracellular signaling cascade
8787GO:0007601IEAProcessvisual perception
8787GO:0008277TASProcessregulation of G-protein coupled receptor protein signaling pathway
8787GO:0009968IEAProcessnegative regulation of signal transduction
8787GO:0050896IEAProcessresponse to stimulus
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
O75916--GnatHPRD04962
O75916--Gnb5HPRD04962
O75916--R9APHPRD04962
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
8787RGS9_HUMANO75916IPR000591DEPPleckstrin/ G-protein, interacting region
8787RGS9_HUMANO75916IPR001770Gprotein-gammaG-protein, gamma subunit
8787RGS9_HUMANO75916IPR000342RGSRegulator of G protein signalling

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