Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:8811
Official Symbol:GALR2
Other Aliases:GALNR2|MGC125983|MGC125984
See related:HGNC:4133|MIM:603691|HPRD:04735
Chromosome:17
Location:17q25.3
Gene Description:galanin receptor 2
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:QTL0183
ORGANISM:human
Entrez Gene ID:8811
Evidence Type:QTL assay
Evidence ID Type:PUBMED
Evidence ID:NA
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 2
KARG ID:QTL0184
ORGANISM:human
Entrez Gene ID:8811
Evidence Type:QTL assay
Evidence ID Type:PUBMED
Evidence ID:NA
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
14428CBCerebellum6.588618755340587.47775030136108
14428CTXCerebral cortex9.22367954254157.91203355789185
14428HIPHippocampal region4.498278617858894.07382488250732
14428HPFHippocampal formation9.489904403686528.00921440124512
14428HYHypothalamus1.985188484191891.44987106323242
14428LSXLateral septal complex0.6363418698310850.426670610904694
14428MBMidbrain1.884900331497192.00241875648499
14428MYMedulla6.630088806152347.45346164703369
14428OLFOlfactory bulb13.970058441162112.4758386611938
14428PPons4.302744865417484.56074714660645
14428PALPallidum2.331461668014531.70422828197479
14428RHPRetrohippocampal region18.949867248535214.3058757781982
14428sAMYStriatum-like amygdalar nuclei0.8555992841720580.584524095058441
14428STRStriatum2.779908180236821.91423833370209
14428STRdStriatum dorsal region2.697043895721441.9219046831131
14428STRvStriatum ventral region5.102231502532963.10207915306091
14428THThalamus2.75994014739992.26145243644714
KARG Evidence 3
KARG ID:QTL0183
Trait:alcohol preference locus, female specific
Peak:70
Peak Marker:D11Mit35
Parents:recombinant Inbreds(RI) AXB and BXA
Evidence ID:9880655
KARG Evidence 4
KARG ID:QTL0184
Trait:alcohol preference locus, female specific
Peak:70
Peak Marker:D11Mit61
Parents:recombinant Inbreds(RI) AXB and BXA
Evidence ID:9880655
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
8811GO:0001584IEAFunctionrhodopsin-like receptor activity
8811GO:0004872IEAFunctionreceptor activity
8811GO:0004966TASFunctiongalanin receptor activity
8811GO:0005886TASComponentplasma membrane
8811GO:0006936TASProcessmuscle contraction
8811GO:0007186IEAProcessG-protein coupled receptor protein signaling pathway
8811GO:0007188TASProcessG-protein signaling, coupled to cAMP nucleotide second messenger
8811GO:0007204TASProcesselevation of cytosolic calcium ion concentration
8811GO:0007268TASProcesssynaptic transmission
8811GO:0007275TASProcessdevelopment
8811GO:0007586TASProcessdigestion
8811GO:0007611TASProcesslearning and/or memory
8811GO:0007631TASProcessfeeding behavior
8811GO:0016021TASComponentintegral to membrane
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_003848.1--GalaninHPRD04735
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
8811GALR2_HUMANO43603IPR001556Bombsn_rcptBombesin receptor
8811GALR2_HUMANO43603IPR001277CXC_4_rcptC-X-C chemokine receptor, type 4
8811GALR2_HUMANO43603IPR000321Delta_opi_rcptDelta opioid receptor
8811GALR2_HUMANO43603IPR000405Galanin_rcptGalanin receptor
8811GALR2_HUMANO43603IPR003907Galnin_2_rcptGalanin 2 receptor
8811GALR2_HUMANO43603IPR000276GPCR_RhodpsnRhodopsin-like GPCR superfamily
8811GALR2_HUMANO43603IPR000611NPY_rcptNeuropeptide Y receptor
8811GALR2_HUMANO43603IPR002286P2_purnocptorP2 purinoceptor
8811GALR2_HUMANO43603IPR008365Prostanoid_rcptProstanoid receptor
8811GALR2_HUMANO43603IPR000586Somatstn_rcptSomatostatin receptor

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