Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:8825
Official Symbol:LIN7A
Other Aliases:LIN-7A|LIN7|MALS-1|TIP-33|VELI1
See related:HGNC:17787|MIM:603380|HPRD:04542
Chromosome:12
Location:12q21
Gene Description:lin-7 homolog A (C. elegans)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0465
ORGANISM:human
Entrez Gene ID:8825
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:85327
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
108030CBCerebellum66.790487289428773.3151721954346
108030CTXCerebral cortex42.40787172317536.7008085250854
108030HIPHippocampal region16.82052659988421.4342074394226
108030HPFHippocampal formation19.432619571685822.5708355903625
108030HYHypothalamus5.477015078067784.94112890958786
108030LSXLateral septal complex38.248223304748537.1519565582275
108030MBMidbrain9.540434837341318.85511088371277
108030MYMedulla14.295974493026716.8628735542297
108030OLFOlfactory bulb47.309758186340348.4779891967773
108030PPons9.7220777273178110.6689224243164
108030PALPallidum12.144890308380111.8318300247192
108030RHPRetrohippocampal region23.202025413513223.5978951454163
108030sAMYStriatum-like amygdalar nuclei14.252825498580914.0311241149902
108030STRStriatum14.822933077812212.3084871768951
108030STRdStriatum dorsal region7.578829944133765.96078613400459
108030STRvStriatum ventral region29.126347064971921.4052805900574
108030THThalamus8.662657141685497.95311069488525
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
8825GO:0005515IPIFunctionprotein binding
8825GO:0005923IEAComponenttight junction
8825GO:0006461TASProcessprotein complex assembly
8825GO:0006887TASProcessexocytosis
8825GO:0015031IEAProcessprotein transport
8825GO:0016020IEAComponentmembrane
8825GO:0019717IEAComponentsynaptosome
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-51678NP_057531.2membrane protein, palmitoylated 6HPRD09509
-10458NP_059345.1BAI1-associated protein 2 isoform 2HPRD05686
NP_004655.1--NR2BHPRD04542
NP_004655.1--VAM1HPRD04542
NP_004655.151678-Membrane protein, palmitoylated 6HPRD04542
NP_004655.164398NP_071919.2membrane protein, palmitoylated 5HPRD09508
NP_004655.164398NP_071919.2membrane protein, palmitoylated 5HPRD04542
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
8825LIN7A_HUMANO14910IPR004172L27L27
8825LIN7A_HUMANO14910IPR001478PDZPDZ/DHR/GLGF

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