Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:8829
Official Symbol:NRP1
Other Aliases:CD304|DKFZp686A03134|DKFZp781F1414|NRP|VEGF165R
See related:HGNC:8004|MIM:602069|HPRD:03642
Chromosome:10
Location:10p12
Gene Description:neuropilin 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0367
ORGANISM:human
Entrez Gene ID:8829
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:18186
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
18186CBCerebellum2.489433765411384.08482491970062
18186CTXCerebral cortex15.362985849380512.7879835367203
18186HIPHippocampal region55.658180236816488.1641883850098
18186HPFHippocampal formation47.637029647827174.1234722137451
18186HYHypothalamus5.578024268150334.97489020228386
18186LSXLateral septal complex20.565342426316.5371832847595
18186MBMidbrain4.329953908920294.794553399086
18186MYMedulla8.8387809991836511.6990802288055
18186OLFOlfactory bulb9.60262000560768.91243100166321
18186PPons5.186530470848086.13809978961945
18186PALPallidum4.242798715829853.55242805182934
18186RHPRetrohippocampal region34.590551376342836.3848695755005
18186sAMYStriatum-like amygdalar nuclei7.664371430873875.99316626787186
18186STRStriatum5.534299731254584.57885706424713
18186STRdStriatum dorsal region3.818762972950943.55503313988447
18186STRvStriatum ventral region2.222238630056381.36614522337914
18186THThalamus7.282559275627149.72124981880188
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
8829GO:0001525IEAProcessangiogenesis
8829GO:0004872IEAFunctionreceptor activity
8829GO:0005021TASFunctionvascular endothelial growth factor receptor activity
8829GO:0005624NRComponentmembrane fraction
8829GO:0007155IEAProcesscell adhesion
8829GO:0007165TASProcesssignal transduction
8829GO:0007267TASProcesscell-cell signaling
8829GO:0007399IEAProcessnervous system development
8829GO:0007411TASProcessaxon guidance
8829GO:0008284TASProcesspositive regulation of cell proliferation
8829GO:0009887TASProcessorgan morphogenesis
8829GO:0016020IEAComponentmembrane
8829GO:0016021IEAComponentintegral to membrane
8829GO:0030154IEAProcesscell differentiation
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-10371NP_006071.1semaphorin 3AHPRD04908
NP_003864.1--PLXNA1HPRD03642
NP_003864.110371-Semaphorin 3AHPRD03642
NP_003864.223129BAA31595.1KIAA0620 proteinBIND180414
NP_003864.210371NP_006071.1semaphorin 3ABIND183369
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
8829IPR000859CUBCUB
8829IPR000421FA58_CCoagulation factor 5/8 type, C-terminal
8829NRP1_HUMANO14786IPR000859CUBCUB
8829NRP1_HUMANO14786IPR000421FA58_CCoagulation factor 5/8 type, C-terminal
8829NRP1_HUMANO14786IPR000998MAMMAM

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