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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry

For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information Gene ID: 8829 Official Symbol: NRP1 Other Aliases: CD304|DKFZp686A03134|DKFZp781F1414|NRP|VEGF165R See related: HGNC:8004|MIM:602069|HPRD:03642 Chromosome: 10 Location: 10p12 Gene Description: neuropilin 1 Gene type: protein-coding Gene Structure: Genomic Context: KARG Evidence 1 KARG ID: EVIC0367 ORGANISM: human Entrez Gene ID: 8829 Evidence Type: Mapping from mouse Evidence ID Type: Entrez Gene Evidence ID: 18186 Addiction Drug: Addiction Drug Detail: Addiction Brain Area: Drug Effects: Fold Change: Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas) Mouse Entrez Gene ID Brain Region Brain Region Detail Expression Level Expression Density 18186 CB Cerebellum 2.48943376541138 4.08482491970062 18186 CTX Cerebral cortex 15.3629858493805 12.7879835367203 18186 HIP Hippocampal region 55.6581802368164 88.1641883850098 18186 HPF Hippocampal formation 47.6370296478271 74.1234722137451 18186 HY Hypothalamus 5.57802426815033 4.97489020228386 18186 LSX Lateral septal complex 20.5653424263 16.5371832847595 18186 MB Midbrain 4.32995390892029 4.794553399086 18186 MY Medulla 8.83878099918365 11.6990802288055 18186 OLF Olfactory bulb 9.6026200056076 8.91243100166321 18186 P Pons 5.18653047084808 6.13809978961945 18186 PAL Pallidum 4.24279871582985 3.55242805182934 18186 RHP Retrohippocampal region 34.5905513763428 36.3848695755005 18186 sAMY Striatum-like amygdalar nuclei 7.66437143087387 5.99316626787186 18186 STR Striatum 5.53429973125458 4.57885706424713 18186 STRd Striatum dorsal region 3.81876297295094 3.55503313988447 18186 STRv Striatum ventral region 2.22223863005638 1.36614522337914 18186 TH Thalamus 7.28255927562714 9.72124981880188 Gene Ontology Gene ID GO ID Evidence GO Type GO Description 8829 GO:0001525 IEA Process angiogenesis 8829 GO:0004872 IEA Function receptor activity 8829 GO:0005021 TAS Function vascular endothelial growth factor receptor activity 8829 GO:0005624 NR Component membrane fraction 8829 GO:0007155 IEA Process cell adhesion 8829 GO:0007165 TAS Process signal transduction 8829 GO:0007267 TAS Process cell-cell signaling 8829 GO:0007399 IEA Process nervous system development 8829 GO:0007411 TAS Process axon guidance 8829 GO:0008284 TAS Process positive regulation of cell proliferation 8829 GO:0009887 TAS Process organ morphogenesis 8829 GO:0016020 IEA Component membrane 8829 GO:0016021 IEA Component integral to membrane 8829 GO:0030154 IEA Process cell differentiation Interaction Information Gene Product ID Interactant Gene ID Interactant Gene Product ID Interactant Gene Product Name Source Source ID - 10371 NP_006071.1 semaphorin 3A HPRD 04908 NP_003864.1 - - PLXNA1 HPRD 03642 NP_003864.1 10371 - Semaphorin 3A HPRD 03642 NP_003864.2 23129 BAA31595.1 KIAA0620 protein BIND 180414 NP_003864.2 10371 NP_006071.1 semaphorin 3A BIND 183369 Domain Information Gene ID Uniprot/Swissprot ID Uniprot/Swissprot ACC Interpro ID Interpro Short Description Interpro Long Description 8829 IPR000859 CUB CUB 8829 IPR000421 FA58_C Coagulation factor 5/8 type, C-terminal 8829 NRP1_HUMAN O14786 IPR000859 CUB CUB 8829 NRP1_HUMAN O14786 IPR000421 FA58_C Coagulation factor 5/8 type, C-terminal 8829 NRP1_HUMAN O14786 IPR000998 MAM MAM © Center for Bioinformatics(CBI), Peking University Any Comments and suggestions to : KARG GROUP.