Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:887
Official Symbol:CCKBR
Other Aliases:CCK-B|GASR
See related:HGNC:1571|MIM:118445|HPRD:00323
Chromosome:11
Location:11p15.4
Gene Description:cholecystokinin B receptor
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0189
ORGANISM:human
Entrez Gene ID:887
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:12426
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
12426CBCerebellum6.395742058753978.36348223686218
12426CTXCerebral cortex83.475082397460970.713659286499
12426HIPHippocampal region5.361109256744385.14883494377136
12426HPFHippocampal formation19.333613395690919.0965671539307
12426HYHypothalamus1.866123437881471.40524324774742
12426LSXLateral septal complex2.554760232567792.53109580278397
12426MBMidbrain4.640815138816834.82947099208832
12426MYMedulla7.923880100250249.01153254508972
12426OLFOlfactory bulb45.392873764038144.9049549102783
12426PPons3.154638528823853.79124164581299
12426PALPallidum1.930913865566251.79205852746964
12426RHPRetrohippocampal region39.878328323364335.9599676132202
12426sAMYStriatum-like amygdalar nuclei10.94276595115668.87942934036255
12426STRStriatum6.212738275527954.91231417655945
12426STRdStriatum dorsal region6.656610250473025.40608692169189
12426STRvStriatum ventral region4.66999948024753.07482028007507
12426THThalamus2.449281871318822.46491581201553
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
887GO:0001584IEAFunctionrhodopsin-like receptor activity
887GO:0004435ISSFunctionphosphoinositide phospholipase C activity
887GO:0004435TASFunctionphosphoinositide phospholipase C activity
887GO:0004872IEAFunctionreceptor activity
887GO:0005886ISSComponentplasma membrane
887GO:0005886TASComponentplasma membrane
887GO:0005887ISSComponentintegral to plasma membrane
887GO:0005887TASComponentintegral to plasma membrane
887GO:0007202ISSProcessphospholipase C activation
887GO:0007202TASProcessphospholipase C activation
887GO:0007204ISSProcesselevation of cytosolic calcium ion concentration
887GO:0007204TASProcesselevation of cytosolic calcium ion concentration
887GO:0007586ISSProcessdigestion
887GO:0007586TASProcessdigestion
887GO:0007600ISSProcesssensory perception
887GO:0007600TASProcesssensory perception
887GO:0007631ISSProcessfeeding behavior
887GO:0007631TASProcessfeeding behavior
887GO:0008283ISSProcesscell proliferation
887GO:0008283TASProcesscell proliferation
887GO:0008284ISSProcesspositive regulation of cell proliferation
887GO:0008284TASProcesspositive regulation of cell proliferation
887GO:0015054IEAFunctiongastrin receptor activity
887GO:0015054ISSFunctiongastrin receptor activity
887GO:0046935ISSFunctionphosphatidylinositol 3-kinase regulator activity
887GO:0046935TASFunctionphosphatidylinositol 3-kinase regulator activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
887GASR_HUMANP32239IPR009126Cholcskin_rcptCholecystokinin receptor
887GASR_HUMANP32239IPR000314Gastrin_rcptGastrin receptor
887GASR_HUMANP32239IPR000276GPCR_RhodpsnRhodopsin-like GPCR superfamily
887GASR_HUMANP32239IPR000832GPCR_secretinGPCR, family 2, secretin-like
887GASR_HUMANP32239IPR000611NPY_rcptNeuropeptide Y receptor
887GASR_HUMANP32239IPR002286P2_purnocptorP2 purinoceptor

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